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Gene Therapy for Huntington’s Disease: The Final Strategy for a Cure?

Byun S, Lee M, Kim M

Huntington’s disease (HD) has become a target of the first clinical trials for gene therapy among movement disorders with a genetic origin. More than 100 clinical trials regarding HD have...
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Opsoclonus-Myoclonus Syndrome as a Heralding Feature of Scrub Typhus: An Illustrative Case with a Video Vignette

Garg D, Dhamija RK

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Task-Specific Dystonia in a Professional Billiard Player

Lee H, Yoo SW, Kim JS

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Re: Comments on “Chorea as a Presentation of SARS-CoV-2 Encephalitis: A Clinical Case Report”

Hassan M, Khan NU, Badshah M

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Resilience and Trauma among Patients with Parkinson’s Disease during the COVID-19 Pandemic

Erro R, Cuoco S, Nigro E, Ragone R, Barone P

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Comment on “Chorea as a Presentation of SARS-CoV-2 Encephalitis: A Clinical Case Report”

Walker RH

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Cortical Subarachnoid Hemorrhage Presenting with Hemibody Dystonic Myoclonus: An Illustrative Case

Ju H, Lee EJ, Lee M, Im K, Kwon KY

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Deep Brain Stimulation for Cockayne Syndrome-Associated Movement Disorder

Domino JS, Gelineau-Morel R, Kaufman C

Cockayne syndrome (CS) is a rare progeroid disorder characterized by multisystem degeneration, including neurological dysfunction, for which deep brain stimulation (DBS) is a proposed treatment. This study represents only the...
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COVID-19 Associated Acute Necrotizing Encephalopathy Presenting as Parkinsonism and Myorhythmia

Ong TL, Nor KM, Yusoff Y, Sapuan S

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Parainfectious Anti-Glial Fibrillary Acidic Protein-Associated Meningoencephalitis

Joo JY, Yoo D, Ahn TB

Movement disorders associated with glial fibrillary acidic protein (GFAP) autoantibodies have rarely been reported as ataxia or tremors. A 32-year-old man with headache and fever, initially diagnosed with viral meningoencephalitis,...
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Dancing Feet Dyskinesia in a Patient with GBA-PD

Olszewska DA, McCarthy A, Soto-Beasley AI, Walton RL, Ross OA, Lynch T

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Current Status of Telemedicine for Parkinson’s Disease in Japan: A Single-Center Cross-Sectional Questionnaire Survey

Ogawa M, Oyama G, Sekimoto S, Hatano T, Hattori N

Objective Using telemedicine is a way to improve the accessibility of specialists for patients with Parkinson’s disease (PD); however, it is not widely used in Japan. We investigated the efficacy...
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Evidence of Inflammation in Parkinson’s Disease and Its Contribution to Synucleinopathy

Lai TT, Kim YJ, Ma Hi, Kim YE

Accumulation of alpha-synuclein (αSyn) protein in neurons is a renowned pathological hallmark of Parkinson’s disease (PD). In addition, accumulating evidence indicates that activated inflammatory responses are involved in the pathogenesis...
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Premonitory Urges Reconsidered: Urge Location Corresponds to Tic Location in Patients With Primary Tic Disorders

Essing J, Jakubovski E, Psathakis N, Cevirme SN, Leckman JF, Müller-Vahl KR

Objective In patients with Tourette syndrome and other primary tic disorders (PTDs), tics are typically preceded by premonitory urges (PUs). To date, only a few studies have investigated the location...
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The Supplementary Motor Complex in Parkinson’s Disease

Rahimpour S, Rajkumar S, Hallett M

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by both motor and nonmotor symptoms. Although the basal ganglia is traditionally the primary brain region implicated in this disease process, this...
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Dance Intervention Using the Feldenkrais Method Improves Motor, and Non-Motor Symptoms and Gait in Parkinson’s Disease: A 12-Month Study

Kang SH, Kim J, Kim I, Moon YA, Park S, Koh SB

Objective The aim of this study was to assess the effects of dancing (using the Feldenkrais method) on motor and non-motor symptoms, quality of life (QoL), and objective parameters of...
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Extensive Leukoencephalopathy in Spastic Paraplegia Type 4: Possible Role of Cerebral Autosomal Arteriopathy With Subcortical Infarcts and Leukoencephelopathy

Jung JH, Seo JH, Lee S, Heo YJ, Kim D, Chung EJ, Oh Si

Despite recent advances in next-generation sequencing, the underlying etiology of adult-onset leukoencephalopathy has been difficult to elucidate. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a representative...
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Constipation is Associated With Mild Cognitive Impairment in Patients With de novo Parkinson’s Disease

Kang SH, Lee J, Koh SB

Objective The association between gastrointestinal (GI) symptoms and cognitive profile in patients with Parkinson’s disease (PD) at diagnosis remains unclear, although GI symptoms and cognitive impairment are highly prevalent in...
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Association of AXIN1 With Parkinson’s Disease in a Taiwanese Population

Fang HS, Chao CY, Wang CC, Fan WL, Huang PJ, Fung HC, Wu YR

Objective A meta-analysis of locus-based genome-wide association studies recently identified a relationship between AXIN1 and Parkinson’s disease (PD). Few studies of Asian populations, however, have reported such a genetic association....
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