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Fatal Broncho-Mediastinal Fistula in a Patient with Non-Small Cell Lung Cancer after Photodynamic Therapy

Heo EY, Kim YJ, Yang SC

Photodynamic therapy (PDT) can be used as palliative therapy to reduce obstructive symptoms in patients with advanced lung cancer. Herein, we report on the case of a patient with fatal...
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Inconclusive Result from CT Guided Transthoracic Needle Aspiration and Biopsy: Affecting Factors and Final Outcome

Lee YJ, Hwang YI, Kim TJ, Yoon HI, Lee KW, Lee CT, Lee JH

PURPOSE: Inconclusive results from computed tomography (CT)-guided transthoracic needle aspiration and biopsy (TNAB) performed for lung lesions presents a clinical dilemma. The purpose of this study was to determine the...
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Clinicopathologic Implications of ALK Gene Copy Number Gain in Non-small Cell Lung Cancer

Yoo SB, Kim H, Xu X, Sun PL, Jin Y, Paik JH, Jheon S, Lee CT, Chung JH

PURPOSE: The anaplastic lymphoma kinase (ALK) gene is a potential molecular target in non-small cell lung carcinoma (NSCLC). The clinicopathologic implication of a change in the ALK gene copy number...
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Array-based Comparative Genomic Hybridization and Its Application to Cancer Genomes and Human Genetics

Cho EK

Microarray comparative genomic hybridization (CGH) has proven to be a specific, sensitive, and rapid technique, with considerable advantages compared to other methods used for analysis of DNA copy number changes....
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Somatostatin Receptors in Lung Cancer: From Function to Molecular Imaging and Therapeutics

Callison J, Walker RC, Massion PP

Lung cancer is a deadly disease that is difficult to diagnose and even more difficult to treat effectively. Many pathways are known to affect tumor growth, and targeting these pathways...
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