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Is multidisciplinary treatment effective for hepatocellular carcinoma with portal vein tumor thrombus?

Choe WH

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Recent updates on the classification of hepatoblastoma according to the International Pediatric Liver Tumors Consensus

Jeong SU, Kang HJ

Hepatoblastoma is the most common pediatric liver malignancy and usually occurs within the first 3 years of life. In recent years, the overall incidence of hepatoblastoma has exhibited the greatest...
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A clinical and pathological update on hepatocellular carcinoma

Renne SL, Tommaso LD

It is estimated that more than 1 million individuals will be affected annually by hepatocellular carcinoma (HCC) by 2025. HCC can be broadly grouped into two major molecular subgroups, each...
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Radioembolization for hepatocellular carcinoma: what clinicians need to know

Choi JW, Kim HC

Transarterial radioembolization (TARE) with yttrium 90 (90Y) has been used in the management of hepatocellular carcinoma (HCC) for more than 10 years in Korea. There are two types of 90Y...
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Sorafenib combined with radiation therapy for advanced hepatocellular carcinoma with portal and hepatic vein invasion extending to the inferior vena cava: a complete response case according to modified RECIST criteria

Cho Y, Kim BH, Kim TH, Koh YH, Park JW

The prognosis of patients with advanced hepatocellular carcinoma (HCC) with tumor thrombus extending to the inferior vena cava (IVC) is extremely poor. Herein, we present a rare case of advanced...
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Concurrent transarterial radioembolization and combination atezolizumab/ bevacizumab treatment of infiltrative hepatocellular carcinoma with portal vein tumor thrombosis: a case report

Park MK, Yu SJ

Treatment options for advanced hepatocellular carcinoma (HCC) have been rapidly evolving. Herein, we describe a patient with advanced HCC and portal vein tumor thrombosis (PVTT) who responded decisively to a...
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Complete response to local therapy for advanced hepatocellular carcinoma with lung metastasis: a case report

Kim D, Park S, Sohn W, Hong HP, Kim BI

The concept of oligometastasis is widely accepted for various types of solid tumors; accordingly, better outcomes can be anticipated with aggressive local interventions. The treatment of advanced hepatocellular carcinoma (HCC)...
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Long-term survival after CCRT and HAIC followed by ALPPS for hepatocellular carcinoma with portal vein invasion: a case report

Kim IJ, Yoo SH, Lee JI, Lee KS, Lee HW, Lim JH

There are various methods for treating advanced hepatocellular carcinoma with portal vein invasion, such as systemic chemotherapy, transarterial chemoembolization, transarterial radioembolization, and concurrent chemoradiotherapy. These methods have similar clinical efficacy...
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The effects of immune checkpoint modulators on the clinical course of patients with resectable hepatocellular carcinoma

An J, Kang HJ, Yu E, Lee HC, Shim JH

Background/Aim: Immune checkpoint proteins regulating T-cell mediated anti-tumor immunity have been reported to affect clinical outcomes in multiple malignancies. This study aimed to investigate the prognostic effect of histological expression...
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Multidisciplinary treatment with immune checkpoint inhibitors for advanced stage hepatocellular carcinoma

Lee A, Lee J, Yang H, Sung SY, Jeon CH, Kim SH, Choi MH, Lee YJ, Chun HJ, Bae SH

Hepatocellular carcinoma (HCC) is a cytotoxic chemotherapy-resistant tumor and most HCCs arise in a background of liver cirrhosis of various causes. Although the IMBrave150 trial showed remarkable advancements in the...
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A case report of advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy and sorafenib combination therapy followed by metastasectomy of lung and muscle metastases

Moon SY, Han SY, Baek YH

Currently, various tyrosine kinase inhibitors and immune checkpoint inhibitors have been suggested in the treatment guidelines for advanced hepatocellular carcinoma (HCC). However, sorafenib was the only systemic drug approved 10...
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Diagnostic performance of serum exosomal miRNA-720 in hepatocellular carcinoma

Jang JW, Kim JM, Kim HS, Kim JS, Han JW, Lee SK, Nam H, Sung PS, Bae SH, Choi JY, Yoon SK

Background/Aim: Hepatocellular carcinoma (HCC) is associated with poor prognosis, largely due to late detection. Highly accurate biomarkers are urgently needed to detect early-stage HCC. Our study aims to explore the...
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