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Immunologic Aspects of Dyslipidemia: a Critical Regulator of Adaptive Immunity and Immune Disorders

Kim D, Chung H, Lee JE, Kim J, Hwang J, Chung Y

Dyslipidemia is a major cause of cardiovascular diseases which represent a leading cause of death in humans. Diverse immune cells are known to be involved in the pathogenesis of cardiovascular...
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Zebrafish Vascular Development: General and Tissue-Specific Regulation

Nakajima H, Chiba A, Fukumoto M, Morooka N, Mochizuki N

Circulation is required for the delivery of oxygen and nutrition to tissues and organs, as well as waste collection. Therefore, the heart and vessels develop first during embryogenesis. The circulatory system...
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Dyslipidemia Fact Sheets in Korea 2020: an Analysis of Nationwide Population-based Data

Cho SMJ, Lee H, Lee HH, Baek J, Heo JE, Joo HJ, Hong SJ, Kim HC, on behalf of the Korean Society of Lipidology and Atherosclerosis (KSoLA) Public Relations Committee

Objective: The Korean Society of Lipid and Atherosclerosis (KSoLA) has published the Dyslipidemia Fact Sheets in Korea 2020 to provide an overview of magnitude and management status of dyslipidemia and...
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Bacterial Postbiotics as Promising Tools to Mitigate Cardiometabolic Diseases

Anhê FF, Jensen BAH, Perazza LR, Tchernof A, Schertzer JD, Marette A

Gut microbes dictate critical features of host immunometabolism. Certain bacterial components and metabolites (termed postbiotics) mitigate cardiometabolic diseases whereas others potentiate pathological processes. In this review, we discuss key aspects...
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The Role of Vitamin D in Adipose Tissue Biology: Adipocyte Differentiation, Energy Metabolism, and Inflammation

Park CY, Han SN

Adipose tissue is composed of diverse cell types and plays a major role in energy homeostasis and inflammation at the local and systemic levels. Adipose tissue serves as the main...
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Iron Reshapes the Gut Microbiome and Host Metabolism

Botta A, Barra NG, Lam NH, Chow S, Pantopoulos K, Schertzer JD, Sweeney G

Compelling studies have established that the gut microbiome is a modifier of metabolic health. Changes in the composition of the gut microbiome are influenced by genetics and the environment, including...
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Cardiovascular Outcomes Comparison of Dipeptidyl Peptidase-4 Inhibitors versus Sulfonylurea as Add-on Therapy for Type 2 Diabetes Mellitus: a Meta-Analysis

Jeon WK, Kang J, Kim HS, Park KW

Objective: Recent studies have raised concern about the cardiovascular safety of dipeptidyl peptidase-4 (DPP4) inhibitors. We performed a systematic review through meta-analysis to compare cardiovascular outcomes of sulfonylurea (SU) versus...
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Effect of Breakfast Consumption and Meal Time Regularity on Nutrient Intake and Cardiometabolic Health in Korean Adults

Yoon SR, Choi M, Kim OY

Objective: Dietary factors are important contributors to obesity and related metabolic disorders. Few studies have evaluated the impact of dietary habits (e.g., breakfast consumption frequency and meal regularity) on metabolic...
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Phosphorylation in Novel Mitochondrial Creatine Kinase Tyrosine Residues Render Cardioprotection against Hypoxia/Reoxygenation Injury

Park N, Marquez J, Garcia MVF, Shimizu I, Lee SR, Kim HK, Han J

Objective: Ischemic cardiomyopathy (ICM) is the leading cause of heart failure. Proteomic and genomic studies have demonstrated ischemic preconditioning (IPC) can assert cardioprotection against ICM through mitochondrial function regulation. Considering...
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