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The Expression of High Mobility Group I (Y) Proteins in Human Breast Cancer

Ryu JW

PURPOSE: The precise mechanisms of tumorigenesis of breast cancer remains unknown in spite of major efforts. Recent studies have shown that High Mobility Group I (Y) Proteins [HMGI(Y)] have an...
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Paget's Disease of the Breast

Kim HT, Lee JY

PURPOSE: Paget's disease of the breast (PDB) occurs in approximately 1~3% of all primary breast carcinomas. This study aimed to determine the optimal surgical treatments for PDB in this study. METHODS:...
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Clinical Analysis of Stage I and II Breast Cancer

Cho YU, Ko YB, Kim SW, Kim SJ, Lee KS, Shin SH, Kim KR

PURPOSE: The combination of conservative surgery and radiotherapy is currently accepted as the preferred treatment for most patents with clinical stage I or II breast cancer. However, there is large...
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The Clinical Significance and Prognosis of Korean Young Age (younger or 35 year old) onset Breast Cancer

Min YK, Kim NR, Cho SJ, Kim A, Bae JW, Koo BH

PURPOSE: Generally, young age onset malignancies show worse prognosis. But is "young age onset" a single prognostic factor for breast cancer, has been controversial. The incidence of breast cancer according...
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Clinical Analysis of Breast Cancer Surgeries in Korea

Son BH, Yoon HS, Kwak HS, Lee PC, Ko BK, Kim JS, Ahn SH

PURPOSE: In Korea, the incidence of breast cancer is continuously growing year after year, and it has become the second most common cancer in females following stomach cancer. This study...
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Combined Peritumoral and Subareolar Injection of Blue Dye Improves Sentinel Lymph Node Localization Rates

Yoon SH, Park HD, Kim JR, Chang ES

PURPOSE: The sentinel lymph node (SLN) biopsy was recently introduced into the treatment of early breast cancer. However, there have been varying degrees of success in identifying the SLNs. Lymphatic...
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Breast Cancer in Third Decade-Does It Really Have a Poor Prognosis?

Lee SD, Park HL, Nam SJ, Yang JH, Ko YH

PURPOSE: The relationship of the age at diagnosis and the prognosis in breast carcinoma remains controversial. However, it is a widely held belief that breast cancer in young women especially...
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Use of the Triple Test for the Patients with Palpable Breast Masses

Jin SI, Han S, Bae BN, Kim KH, Kim HJ, Kim YD, Kim HY

PURPOSE: Breast mass - the most common occurences in the breast must be managed by a method that provides both the best medical and cosmetic results. METHODS: Two...
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The Impact of Patient Age upon Locoregional and Systemic Failures after Breast Conservation Therapy: Comparison of the Results from the Groups above and below 35 Years

Kim SI, Park BW, Lee KS

PURPOSE: It has long been controversial whether breast cancer of the younger women is more aggressive than that of older women and remains unclear whether the dismal outcome seen in...
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Significance on the Expression of Cyclin, MIB-1 in Benign and Malignant Papillary Lesion of the Breast

An WS, Kim TH, Lee JY

PURPOSE: It is difficult at times to differentiate between a papillary carcinoma and benign papilloma of the breast, and papillomas can undergo malignant transformation. The authors investigated the expression of...
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Clinical Significance of Rotter's Nodes in Patients with Breast Carcinomas

Sin JW, Lee SJ, Jeong KH, Kwun KB

PURPOSE: Rotter's nodes are removed in the course of a radical mastectomy, however they are not routinely removed in a modified radical mastectomy and breast conserving surgery, although they can...
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A Study on Modified Triple Test for Palpable Breast Mass

Kim JK, Song YJ, Cho SI, Yun HY, Yoon HS

PURPOSE: The "triple test" (TT) which consists of a physical examination (PE), mammography (MMG), and fine needle aspiration (FNA) has been used for diagnosing a palpable breast mass. However, the...
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Immediate Free TRAM Flap Reconstruction after Mastectomy in Breast Cancer Patients

Cho SJ, Nam YS, Jung PJ, Baik HK, Park HK, Jung YG, Ahn HC

PURPOSE: Despite the advocation of a breast conserving approach to the treatment of breast cancer, many women continue to surgically require or choose mastectomy for the treatment of breast cancer....
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Loss of Expression of the PTEN Gene Product in the Infiltrating Ductal Carcinoma of the Breast and Its Relationship with Clinicopathologic Factors

Park SB, Choi TY, Cha SJ, Lee TJ, Park SI, Lim HM, Park SJ, Chi KC

PURPOSE: PTEN is a novel tumor suppressor gene located on chromosomal band 10q23.3. The detection of PTEN mutations in Cowden disease and in breast carcinoma cell lines suggests that PTEN...
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The Antiproliferating Effect of Diallyl Disulfide from Garlic on the Human Breast Cancer Cell Line (MCF-7)

Park HL, Yang JH, Bae JW, Lee KP, Koo BH

PURPOSE: Diallyl disulfide (DADS), an organosulfur compound in garlic, has been reported to be effective in inhibiting the growth of several human tumor cell lines. The aim of this study...
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