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The 34th Annual Meeting of the Korean Society of Gynecologic Oncology 2019: meeting report

Yim GW, Suh DH, Kim JW, Kim SC, Kim YT

The 34th Annual Meeting of Korean Society of Gynecologic Oncology (KSGO) was held in Busan, Korea from 26 to 27 April. Around 460 Korean and international clinicians gathered in Busan...
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Adjuvant chemotherapy in locally advanced cervical cancer: the ceiling remains unbroken

Gupta S

No abstract available.
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Clinical significance of variants of unknown significances in BRCA genes

Choi MC

No abstract available.
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The influence of BRCA variants of unknown significance on cancer risk management decision-making

Chern JY, Lee SS, Frey MK, Lee J, Blank SV

OBJECTIVE: To compare gynecological cancer risk management between women with BRCA variants of unknown significance (VUS) to women with negative genetic testing METHODS: Ninety-nine patients whose BRCA genetic testing yielded VUS...
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Actinomycin D shortage in the Brazilian market: new challenges for successful treatment of gestational trophoblastic neoplasia

Paulino E, de Melo AC

No abstract available.
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The current situation of the levonorgestrel intrauterine system (LNG-IUS) in conservative treatment for patients with early-stage endometrial cancer and atypical hyperplasia

Chen X

No abstract available.
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Uterine smooth muscle tumor of uncertain malignant potential: fertility and clinical outcomes

Şahin H, Karatas F, Coban G, Özen O, Erdem O, Onan MA, Ayhan A

OBJECTIVE: In this study, we aimed to evaluate the clinicopathological features, obstetric, and oncological outcomes of patients diagnosed with a uterine smooth muscle tumors of uncertain malignant potential (STUMP). METHODS: A...
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Clinical comparison between neuroendocrine and endometrioid type carcinoma of the uterine corpus

Mei S, Gibbs J, Economos K, Lee YC, Kanis MJ

OBJECTIVE: To compare the clinicopathologic features and survival outcomes of neuroendocrine tumor of the uterine corpus (NET-U) to endometrioid type endometrial carcinoma (EC). METHODS: From 1993 to 2012, the Surveillance, Epidemiology...
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Pharmacokinetics of cisplatin during open and minimally-invasive secondary cytoreductive surgery plus HIPEC in women with platinum-sensitive recurrent ovarian cancer: a prospective study

Petrillo M, Zucchetti , Cianci S, Morosi L, Ronsini C, Colombo A, D'Incalci , Scambia G, Fagotti A

OBJECTIVE: Evidences from animal models seem to suggest that minimally invasive surgery may enhance cisplatin diffusion when the drug is administered in the context of post-operative hyperthermic intraperitoneal chemotherapy (HIPEC)....
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Efficacy and fertility outcomes of levonorgestrel-releasing intra-uterine system treatment for patients with atypical complex hyperplasia or endometrial cancer: a retrospective study

Leone Roberti Maggiore U, Martinelli F, Dondi G, Bogani G, Chiappa V, Evangelista MT, Liberale V, Ditto A, Ferrero S, Raspagliesi F

OBJECTIVE: To investigate the efficacy of levonorgestrel-releasing intra-uterine system (LNG-IUS) treatment in patients affected by atypical complex hyperplasia/endometrial cancer (ACH/EC) wishing to preserve their fertility and to present fertility outcomes...
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A randomized controlled trial comparing concurrent chemoradiation versus concurrent chemoradiation followed by adjuvant chemotherapy in locally advanced cervical cancer patients: ACTLACC trial

Tangjitgamol S, Tharavichitkul E, Tovanabutra C, Rongsriyam K, Asakij T, Paengchit , Sukhaboon , Penpattanagul S, Kridakara , Hanprasertpong J, Chomprasert K, Wanglikitkoon S, Atjimakul , Pariyawateekul P, Katanyoo K, Tanprasert P, Janweerachai W, Sangthawan D, Khunnarong J, Chottetanaprasith T, Supawattanabodee B, Lertsanguansinchai P, Srisomboon J, Isaranuwatchai W, Lorvidhaya V

OBJECTIVE: To compare response rate and survivals of locally advanced stage cervical cancer patients who had standard concurrent chemoradiation therapy (CCRT) alone to those who had adjuvant chemotherapy (ACT) after...
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Impact of vaginal brachytherapy in intermediate and high-intermediate risk endometrial cancer: a multicenter study from the FRANCOGYN group

Reboux PA, Azaïs H, Canova CH, Bendifallah S, Ouldamer L, Raimond E, Hudry D, Coutant C, Graesslin , Touboul C, Collinet P, Bricou A, Huchon C, Daraï E, Ballester , Lévêque , Lavoué V, Koskas M, Uzan C, Canlorbe G

OBJECTIVE: According to recent European Society of Medical Oncology, European Society of Gynaecological Oncology and European Society of Radiotherapy and Oncology guidelines, adjuvant vaginal brachytherapy (VB) is optional in patients...
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Early experiences with PD-1 inhibitor treatment of platinum resistant epithelial ovarian cancer

Normann MC, Türzer M, Diep LM, Oldenburg , Gajdzik B, Solheim O, Rud E

OBJECTIVE: In this study, we evaluated the toxicity and clinical efficacy of nivolumab, a programmed cell death protein 1 (PD-1) inhibitor, on patients with platinum resistant ovarian cancer. METHODS: Every second...
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Conservative hysteroscopic treatment of stage I well differentiated endometrial cancer in patients with high surgical risk: a pilot study

Casadio P, Guasina F, Talamo MR, Paradisi R, Morra C, Magnarelli G, Seracchioli R

OBJECTIVE: To report hysteroscopic treatment combined with levonorgestrel-releasing intrauterine device (LNG-IUD) to treat women with early well differentiated endometrial cancer (EC) at high surgical risk. METHODS: Nine women diagnosed with stage...
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Prognostic importance of atypical endometriosis with architectural hyperplasia versus cytologic atypia in endometriosis-associated ovarian cancer

Ñiguez Sevilla I, Machado Linde F, Marín Sánchez MdP, Arense JJ, Torroba A, Nieto Díaz A, Sánchez Ferrer ML

OBJECTIVE: Patients with endometriosis are at increased risk of ovarian cancer. It has been suggested that atypical endometriosis is a precursor lesion of endometriosis-associated ovarian cancer (EAOC). The aim of...
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Stage and histology of cervical cancer in women under 25 years old

Vale DB, Cavalcante LA, Andrade LA, Teixeira J, Menin TL, Zeferino L

OBJECTIVE: To evaluate the histological and stage characteristics of cervical cancer in women under 25 years old, and to compare them with older women. METHODS: Cross-sectional study of cases from the...
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Effects of hormone therapy on recurrence in endometrial cancer survivors: a nationwide study using the Korean Health Insurance Review and Assessment Service database

Cho HW, Ouh YT, Lee JK, Hong JH

OBJECTIVE: The aim of this study was to verify the effects of hormone therapy (HT) on recurrence in endometrial cancer (EC) survivors using the Korean Health Insurance Review and Assessment...
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A pilot study of gonadotropin-releasing hormone agonist combined with aromatase inhibitor as fertility-sparing treatment in obese patients with endometrial cancer

Zhang Z, Huang H, Feng F, Wang J, Cheng N

OBJECTIVE: This study aims to evaluate the effects and pregnancy outcomes of gonadotropin-releasing hormone agonist (GnRH agonist) combined with aromatase inhibitor (AI) in preserving the fertility of obese women with...
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Human papillomavirus genotype-specific risk in cervical carcinogenesis

So KA, Lee IH, Lee KH, Hong SR, Kim YJ, Seo HH, Kim TJ

OBJECTIVE: To evaluate the risk of genotype-specific human papillomavirus (HPV) infections for the spectrum of cervical carcinogenesis and the distribution of HPV types according to age and different cervical lesions METHODS:...
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Prediction of survival outcomes in patients with epithelial ovarian cancer using machine learning methods

Paik ES, Lee JW, Park JY, Kim JH, Kim M, Kim TJ, Choi CH, Kim BG, Bae DS, Seo SW

OBJECTIVES: The aim of this study was to develop a new prognostic classification for epithelial ovarian cancer (EOC) patients using gradient boosting (GB) and to compare the accuracy of the...
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