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Cancer Patient’s Distress: Mainly about Depression and Anxiety

Lee HJ

Distress can occur at any stage of the cancer continuum—from diagnosis through treatment and into survivorship—and can be attributed to various factors. This article examines the multifactorial causes of distress...
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Targeted Therapy for Pancreatic Cancer: Focus on KRAS

Keum J, Lee SH

Pancreatic cancer is among the most aggressive malignancies, with a 5-year overall survival rate of approximately 10%. Despite the establishment of gemcitabine- and fluoropyrimidine-based combination chemotherapy as the standard of...
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Treatment Strategies for MSI-H/dMMR Metastatic Colorectal Cancer

Yoon J, Song HH

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Upper Gastrointestinal Neoplasms in Familiar Adenomatous Polyposis

Noh JH

Familial adenomatous polyposis (FAP) is an autosomal dominant genetic disorder caused by mutations in the adenomatous polyposis coli gene. FAP is characterized by the development of hundreds to thousands of...
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Prevalence and Characteristics of Colorectal Serrated Polyps

Na SY

Colorectal serrated polyps (SP) are precancerous lesions characterized by a saw-tooth appearance in the colonic epithelium that contribute to colorectal cancer (CRC) development via the serrated pathway. CRC is the...
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Guidelines for the Storage, Isolation, and Characterization of Extracellular Vesicle Research

Chae S, Jung W, Lee YJ, Choi D

Extracellular vesicles (EVs) are lipid bilayer-enclosed particles that contain diverse molecular components, such as proteins, nucleic acids, and lipids. EVs reflect the state of their cell of origin in intercellular...
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Management and Outcomes of Adverse Events Following Immune Checkpoint Inhibitor Treatment in Patients with Hepatocellular Carcinoma

Lee SK, Kim BH

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality, is often diagnosed at an advanced stage. As a result, approximately half of patients with HCC received systemic therapy during the...
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Harnessing Milk-derived Extracellular Vesicles for Oral Drug Delivery and Therapeutic Application

Jang H, Yang Y

Extracellular vesicles (EVs) have emerged as highly promising nanocarriers for drug delivery, due to their biocompatibility, stability, and natural cell-targeting capabilities. Among the various sources of EVs, milk-derived EVs (MDEVs)...
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Exosome-based Therapeutics for Inflammatory Bowel Disease

Kang SJ, Rhee WJ

Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is a chronic inflammatory disorder that significantly diminishes the quality of life of patients. Current pharmacological treatments are often limited...
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In-stent Radiofrequency Ablation for Tumor Ingrowth Causing Self-expandable Metal Stent Occlusion

Park N

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Giant Brunner’s Gland Adenoma Diagnosed by Endoscopic Ultrasound-guided Fine-needle Biopsy

Park JH

Brunner’s gland adenoma is a rare benign duodenal tumor often discovered incidentally during endoscopy. A 48-year-old male presented with weight loss, dizziness, and melena. Endoscopic examination revealed a large, smooth-surfaced,...
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