- Steamed Ginger Extract Exerts Anti-inflammatory Effects in Helicobacter pylori-infected Gastric Epithelial Cells through Inhibition of NF-κB
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Song MY, Lee DY, Park SY, Seo SA, Hwang JS, Heo SH, Kim EH
- KMID: 2528097
- J Cancer Prev.
- 2022 Mar;27(1):77-77.
- doi: 10.15430/JCP.2022.27.1.77
No abstract available. -
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- Genetic Alterations and Microenvironment that Drive Malignant Progression of Colorectal Cancer: Lessons from Mouse and Organoid Models
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Nakayama M, Wang D, Kok SY, Oshima H, Oshima M
- KMID: 2528079
- J Cancer Prev.
- 2022 Mar;27(1):1-6.
- doi: 10.15430/JCP.2022.27.1.1
Comprehensive genome analyses have identified frequently mutated genes in human colorectal cancers (CRC). These include APC, KRAS, SMAD4, TP53, and FBXW7. The biological functions of the respective gene products in cell proliferation and homeostasis have... -
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- Mannose Attenuates Colitis-Associated Colorectal Tumorigenesis by Targeting Tumor-Associated Macrophages
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Liu Q, Li X, Zhang H, Li H
- KMID: 2528087
- J Cancer Prev.
- 2022 Mar;27(1):31-41.
- doi: 10.15430/JCP.2022.27.1.31
Mannose has recently drawn extensive attention for its substantial anti-cancer activities, but the underlying mechanism remains largely unclear. The aim of this study was to investigate the effects of mannose... -
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- Non-canonical vs. Canonical Functions of Heme Oxygenase-1 in Cancer
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Jagadeesh ASV, Fang X, Kim SH, Guillen-Quispe YN, Zheng J, Surh YJ, Kim SJ
- KMID: 2528081
- J Cancer Prev.
- 2022 Mar;27(1):7-15.
- doi: 10.15430/JCP.2022.27.1.7
Heme oxygenase-1 (HO-1) is a critical stress-responsive enzyme that has antioxidant and anti-inflammatory functions. HO-1 catalyzes heme degradation, which gives rise to the formation of carbon monoxide (CO), biliverdin, and... -
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- Gene Expression Changes by Diallyl Trisulfide Administration in Chemically-induced Mammary Tumors in Rats
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Hahm ER, Singh SV
- KMID: 2528086
- J Cancer Prev.
- 2022 Mar;27(1):22-30.
- doi: 10.15430/JCP.2022.27.1.22
Diallyl trisulfide (DATS) was shown to be a potent inhibitor of luminal-type MCF-7 xenograft growth in vivo. The present study was conducted to determine the preventive effect of DATS administration... -
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- Protocatechuic Acid, a Gut Bacterial Metabolite of Black Raspberries, Inhibits Adenoma Development and Alters Gut Microbiome Profiles in Apc Min/+ Mice
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Dong A, Lin CW, Echeveste CE, Huang YW, Oshima K, Yearsley M, Chen X, Yu J, Wang LS
- KMID: 2528091
- J Cancer Prev.
- 2022 Mar;27(1):50-57.
- doi: 10.15430/JCP.2022.27.1.50
Administration of black raspberries (BRBs) and their anthocyanin metabolites, including protocatechuic acid (PCA), has been demonstrated to exert chemopreventive effects against colorectal cancer through alteration of innate immune cell trafficking,... -
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- Nuclear Localization of Fibroblast Growth Factor Receptor 1 in Breast Cancer Cells Interacting with Cancer Associated Fibroblasts
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Suh J, Kim DH, Kim SJ, Cho NC, Lee YH, Jang JH, Surh YJ
- KMID: 2528095
- J Cancer Prev.
- 2022 Mar;27(1):68-76.
- doi: 10.15430/JCP.2022.27.1.68
Cancer-associated fibroblasts (CAFs) represent a major component of the tumor microenvironment and interplay with cancer cells by secreting cytokines, growth factors and extracellular matrix proteins. When estrogen receptor-negative breast cancer... -
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- Ethanol Extract of Chaenomeles sinensis Inhibits the Development of Benign Prostatic Hyperplasia by Exhibiting Anti-oxidant and Anti-inflammatory Effects
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Kang JS, Zhao XY, Lee JH, Lee JS, Keum YS
- KMID: 2528088
- J Cancer Prev.
- 2022 Mar;27(1):42-49.
- doi: 10.15430/JCP.2022.27.1.42
Chaenomeles sinensis is known to inhibit the development and progression of many age-related diseases, but the underlying molecular mechanisms are largely unclear. In the present study, we observed that the... -
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- Role of Oral Microbiota in Carcinogenesis: A Short Review
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Issrani R, Reddy J, Dabah THEM, Prabhu N
- KMID: 2528083
- J Cancer Prev.
- 2022 Mar;27(1):16-21.
- doi: 10.15430/JCP.2022.27.1.16
A strong and healthy microbiome is responsible for homeostasis between the host and microbiota which is necessary to achieve the normal functioning of the body. Dysbiosis provokes prevalence of pathogenic... -
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- Involvement of AMP-activated Protein Kinase α/ Nuclear Factor (Erythroid-derived 2) Like 2-iniatived Signaling Pathway in Cytoprotective Effects of Wasabi 6-(Methylsulfinyl) Hexyl Isothiocyanate
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Pan X, Xie K, Chen K, He Z, Sakao K, Hou DX
- KMID: 2528093
- J Cancer Prev.
- 2022 Mar;27(1):58-67.
- doi: 10.15430/JCP.2022.27.1.58
6-(Methylsulfinyl) hexyl isothiocyanate (6-MSITC) is an active ingredient present in Wasabi, which is a popular pungent spice used in Japanese cuisine. Our previous studies suggested that the primary antioxidant activity... -
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