- Primary Cancer Prevention by Green Tea, and Tertiary Cancer Prevention by the Combination of Green Tea Catechins and Anticancer Compounds
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Fujiki H, Sueoka E, Watanabe T, Suganuma M
- KMID: 2171312
- J Cancer Prev.
- 2015 Mar;20(1):1-4.
- doi: 10.15430/JCP.2015.20.1.1
Green tea is a daily beverage, a non-oxidized non-fermented product containing at least four green tea catechins. Considering our first results when repeated applications of (-)-epigallocatechin gallate (EGCG) prevented tumor... -
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- Review of Atrophic Gastritis and Intestinal Metaplasia as a Premalignant Lesion of Gastric Cancer
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Park YH, Kim N
- KMID: 2171315
- J Cancer Prev.
- 2015 Mar;20(1):25-40.
- doi: 10.15430/JCP.2015.20.1.25
Atrophic gastritis (AG) and intestinal metaplasia (IM) are the main precursor lesions of gastric cancer as the incidence of gastric cancer increases in the gastric mucosa involved with AG and... -
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- Endocrine-disrupting Chemicals: Review of Toxicological Mechanisms Using Molecular Pathway Analysis
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Yang O, Kim HL, Weon JI, Seo YR
- KMID: 2171314
- J Cancer Prev.
- 2015 Mar;20(1):12-24.
- doi: 10.15430/JCP.2015.20.1.12
Endocrine disruptors are known to cause harmful effects to human through various exposure routes. These chemicals mainly appear to interfere with the endocrine or hormone systems. As importantly, numerous studies... -
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- Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells by Inducing Apoptosis
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Jeong CH
- KMID: 2171318
- J Cancer Prev.
- 2015 Mar;20(1):57-63.
- doi: 10.15430/JCP.2015.20.1.57
BACKGROUND: Therapeutic approach by treatment with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) like gefitinib or erlotinib to non-small cell lung cancer (NSCLC) patients has been limited due to emergence... -
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- Identification of a New Selective Chemical Inhibitor of Mutant Isocitrate Dehydrogenase-1
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Kim HJ, Choi BY, Keum YS
- KMID: 2171321
- J Cancer Prev.
- 2015 Mar;20(1):78-83.
- doi: 10.15430/JCP.2015.20.1.78
BACKGROUND: Recent genome-wide sequencing studies have identified unexpected genetic alterations in cancer. In particular, missense mutations in isocitrate dehydrogenase-1 (IDH1) at arginine 132, mostly substituted into histidine (IDH1-R132H) were observed... -
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- Small Molecule Inhibitors to Disrupt Protein-protein Interactions of Heat Shock Protein 90 Chaperone Machinery
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Seo YH
- KMID: 2171313
- J Cancer Prev.
- 2015 Mar;20(1):5-11.
- doi: 10.15430/JCP.2015.20.1.5
Heat shock protein 90 (Hsp90) is an adenosine triphosphate dependent molecular chaperone in eukaryotic cells that regulates the activation and maintenance of numerous regulatory and signaling proteins including epidermal growth... -
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- Anthocyanins From the Fruit of Vitis coignetiae Pulliat Potentiate the Cisplatin Activity by Inhibiting PI3K/Akt Signaling Pathways in Human Gastric Cancer Cells
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Lu JN, Lee WS, Nagappan A, Chang SH, Choi YH, Kim HJ, Kim GS, Ryu CH, Shin SC, Jung JM, Hong SC
- KMID: 2171317
- J Cancer Prev.
- 2015 Mar;20(1):50-56.
- doi: 10.15430/JCP.2015.20.1.50
BACKGROUND: Cisplatin (cis-diaminedichloroplatinum, CDDP) is a widely used chemotherapeutic agent for the treatment of many cancers. However, initial resistance to CDDP is a serious problem in treating these cancers. Vitis... -
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- Carnosic Acid Inhibits Lipid Accumulation in 3T3-L1 Adipocytes Through Attenuation of Fatty Acid Desaturation
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Park MY, Sung MK
- KMID: 2171316
- J Cancer Prev.
- 2015 Mar;20(1):41-49.
- doi: 10.15430/JCP.2015.20.1.41
BACKGROUND: Excess body fat accumulation contributes to the development of metabolic disorders that can cause adverse health effects. Carnosic acid (CA), a major bioactive component of rosemary (Rosemarinus officinalis), has... -
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- A Controlled, Randomized, Double-blind Trial to Evaluate the Effect of Vegetables and Whole Grain Powder That Is Rich in Dietary Fibers on Bowel Functions and Defecation in Constipated Young Adults
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Woo HI, Kwak SH, Lee Y, Choi JH, Cho YM, Om AS
- KMID: 2171319
- J Cancer Prev.
- 2015 Mar;20(1):64-69.
- doi: 10.15430/JCP.2015.20.1.64
BACKGROUND: This study evaluated the effect of vege-powder (VP), mainly consisted of chicory, broccoli, and whole grains, on bowel habit improvement and constipation alleviation. METHODS: Using the Roman standard II, 96... -
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- Clinical Implication of p16, Ki-67, and Proliferating Cell Nuclear Antigen Expression in Cervical Neoplasia: Improvement of Diagnostic Accuracy for High-grade Squamous Intraepithelial Lesion and Prediction of Resection Margin Involvement on Conization Specimen
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Kim TH, Han JH, Shin E, Noh JH, Kim HS, Song YS
- KMID: 2171320
- J Cancer Prev.
- 2015 Mar;20(1):70-77.
- doi: 10.15430/JCP.2015.20.1.70
BACKGROUND: Cervical intraepithelial neoplasia (CIN) grading is subjective and affected by substantial rates of discordance among pathologists. Although the use of p16INK4a (p16) staining has been proven to improve diagnostic... -
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