- A Case of von Gierke Disease
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Joe YA, Song MY, Cho B, Lee SJ, Sung IK, Lee KS
- KMID: 2335312
- J Korean Pediatr Soc.
- 1997 Dec;40(12):1756-1756.
von Gierke disease (type Ia glycogen storage disease) is an inherited disease associated with accumulation of glycogen in the liver, kidney, intestine and erythrocytes due to the defect of glucose-6-phosphatase... -
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- Enhancing Anti-Cancer Therapy with Selective Autophagy Inhibitors by Targeting Protective Autophagy
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Lee MJ, Park JS, Jo SB, Joe YA
- KMID: 2537576
- Biomol Ther.
- 2023 Jan;31(1):1-15.
- doi: 10.4062/biomolther.2022.153
Autophagy is a process of eliminating damaged or unnecessary proteins and organelles, thereby maintaining intracellular homeostasis. Deregulation of autophagy is associated with several diseases including cancer. Contradictory dual roles of... -
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- A ROCK Inhibitor Blocks the Inhibitory Effect of Chondroitin Sulfate Proteoglycan on Morphological Changes of Mesenchymal Stromal/Stem Cells into Neuron-Like Cells
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Lim HS, Joe YA
- KMID: 2170662
- Biomol Ther.
- 2013 Nov;21(6):447-453.
Chondroitin sulfate proteoglycan (CSPG) inhibits neurite outgrowth of various neuronal cell types, and CSPG-associated inhibition of neurite outgrowth is mediated by the Rho/ROCK pathway. Mesenchymal stromal/stem cells (MSCs) have the... -
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- Purification and characterization of recombinant murine endostatin in E. coli
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You WK, So SH, Lee H, Park SY, Yoon MR, Chang SI, Kim HK, Joe YA, Hong YK, Chung SI
- KMID: 1029927
- Exp Mol Med.
- 1999 Dec;31(4):197-202.
Endostatin, a carboxyl-terminal fragment of collagen XVIII is known as an anti-angiogenic agent, that specifically inhibits the proliferation of endothelial cell and the growth of several primary tumor.... -
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- Modulation of Autophagy is a Potential Strategy for Enhancing the Anti-Tumor Effect of Mebendazole in Glioblastoma Cells
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Jo SB, Sung SJ, Choi HS, Park JS, Hong YK, Joe YA
- KMID: 2534712
- Biomol Ther.
- 2022 Nov;30(6):616-624.
- doi: 10.4062/biomolther.2022.122
Mebendazole (MBZ), a microtubule depolymerizing drug commonly used for the treatment of helminthic infections, has been suggested as a repositioning candidate for the treatment of brain tumors. However, the efficacy... -
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- Potentials and limitations of adenovirus-p53 gene therapy for brain tumors
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Hong YK, Joe YA, Yang YJ, Lee KS, Son BC, Jeun SS, Chung DS, Cho KK, Park CK, Kim MC, Kim HK, Yung WK, Kang JK
- KMID: 1128631
- J Korean Med Sci.
- 2000 Jun;15(3):315-322.
- doi: 10.3346/jkms.2000.15.3.315
We investigated the antineoplastic potentials of recombinant adenovirus containing wild-type p53 cDNA (Ad5CMV-p53) for malignant gliomas. In four human glioma cell lines (U-251 and LG expressing endogenous mutant p53, and... -
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- Production of Soluble VEGF Receptor Mutants for Inhibition of Angiogenesis
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Yun SY, Hong YK, Lee Y, Kim K, Kim HK, Joe YA
- KMID: 2175025
- J Korean Cancer Assoc.
- 2000 Jun;32(3):595-604.
PURPOSE: Vascular endothelial growth factor (VEGF) is a potent angiogenic factor of many solid tumors, promoting vascularization and formation of metastases. In an attempt to generate effective VEGF inhibitors, the authors constructed... -
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- Autophagy Is a Potential Target for Enhancing the Anti-Angiogenic Effect of Mebendazole in Endothelial Cells
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Sung SJ, Kim HK, Hong YK, Joe YA
- KMID: 2432075
- Biomol Ther.
- 2019 Jan;27(1):117-125.
- doi: 10.4062/biomolther.2018.222
Mebendazole (MBZ), a microtubule depolymerizing drug commonly used for the treatment of helminthic infections, has recently been noted as a repositioning candidate for angiogenesis inhibition and cancer therapy. However, the... -
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- Differential inhibition of endothelial cell proliferation and migration by urokinase subdomains: amino-terminal fragment and kringle domain
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Kim KS, Hong YK, Lee Y, Shin JY, Chang SI, Chung SI, Joe YA
- KMID: 1119342
- Exp Mol Med.
- 2003 Dec;35(6):578-585.
The serine protease urokinase-type plasminogen activator (uPA) is implicated in pericellular proteolysis in a variety of physiological and pathological processes including angiogenesis and tumor metastasis. The kringle domain of uPA... -
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- In vitro Differentiation of Endothelial Precursor Cells Derived from Umbilical Cord Blood
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Joe YA, Baek SH, Park HE, Lee YH, Kwon HK, Kim YJ, Lee SY, Seung KB, Chae JS, Kim JH, Hong SJ, Choi KB
- KMID: 1858691
- Korean Circ J.
- 2002 Aug;32(8):646-654.
- doi: 10.4070/kcj.2002.32.8.646
BACKGROUND AND OBJECTIVES: Ex vivo expansion of endothelial cells is important when applying cell therapy to therapeutic angiogenesis in ischemic tissues. Endothelial precursor cells (EPCs) from the umbilical cord blood... -
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