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Changes in the DSM Diagnostic Concept of Schizophrenia: From 1980 to 2013

Jo YT, Joo YH

Schizophrenia has been conceptualized as a biologically caused mental disease. However, its causes and pathophysiology have not yet been clearly defined. Unlike physical diseases that are defined using specific biomarkers,...
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Association of the First Antipsychotic Treatment Duration With the Re-Initiation of Treatment in Schizophrenia: A National Health Insurance Data-Based Study

Song M, Lee J, Kim H, Ahn S, Choi YJ, Jo YT, Joo SW

Objectives: The optimal duration of maintenance treatment for patients with first-episode schizophrenia (FES) remains unclear. We examined the first antipsychotic treatment duration and its association with re-initiation of treatment using...
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Inflammatory Cytokines and Cognition in Alzheimer’s Disease and Its Prodrome

Seong SJ, Kim KW, Song JY, Park KJ, Jo YT, Han JH, Yoo KH, Jo HJ, Hwang JY

Objective The aim of this study was to investigate the association between blood levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) and cognitive impairments among elderly individuals. Methods Peripheral concentration...
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Characteristics of Delirium in Patients with Hearing Disturbances

Jo YT, Joo SW, Lee J, Joo YH

OBJECTIVES: Several studies have delineated the relationship between hearing disturbances and the prevalence or characteristics of psychotic symptoms; however, most of those studies focused on psychiatric patients and not general...
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Additive Burden of Abnormal Diffusivity in the Brainwith Schizophrenia: A Diffusion Tensor Imaging Studywith Public Neuroimaging Data

Jo YT, Lee J, Joo SW, Kim H, Shon SH, Yoon W, Hong Y

Objective Diffusion tensor imaging has been extensively applied to schizophrenia research. In this study, we counted the number of abnormal brain regions with altered diffusion measures in patients with schizophrenia to...
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Recent Insights in the Treatment for Clinical High Risk for Psychosis and Recent Onset Psychosis

Park S, Jo YT, Lee JS, Lee J, Park IH

Objectives: This study aims to assess the effectiveness of early interventions in preventing psychosis transition, promoting remission, and reducing hospitalization rates in individuals at high risk for psychosis and those...
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