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The effect of combined treatment with cisplatin and histone deacetylase inhibitors on HeLa cells

Jin KL, Park JY, Noh EJ, Hoe KL, Lee JH, Kim JH, Nam JH

OBJECTIVE: To investigate the combined effects of cisplatin and the histone deacetylase (HDAC) inhibitors suberoylanilide hydroxamic acid (SAHA) or sirtinol on HeLa cells and assess the mechanism underlying HDAC inhibitor-cisplatin...
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Expression profile of histone deacetylases 1, 2 and 3 in ovarian cancer tissues

Jin KL, Pak JH, Park JY, Choi WH, Lee JY, Kim JH, Nam JH

OBJECTIVE: To investigate the expression levels of histone deacetylase (HDAC) 1, 2, and 3 in ovarian cancer tissues and normal ovarian tissues. METHODS: Randomly assigned each of six patients with...
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