- Porous Microcarrier-Enabled Three-Dimensional Culture of Chondrocytes for Cartilage Engineering: A Feasibility Study
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Jin GZ, Kim HW
- KMID: 2361007
- Tissue Eng Regen Med.
- 2016 Jun;13(3):235-241.
- doi: 10.1007/s13770-016-0038-6
Cartilage repair is substantially intractable due to poor self-healing ability. Porous microspheres can be a fascinating three-dimensional matrix for cell culture and injectable carrier in cartilage engineering. In this study,... -
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- Research Models of the Nanoparticle-Mediated Drug Delivery across the Blood–Brain Barrier
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Li QY, Lee JH, Kim HW, Jin GZ
- KMID: 2522567
- Tissue Eng Regen Med.
- 2021 Dec;18(6):917-930.
- doi: 10.1007/s13770-021-00356-x
Brain diseases and damages come in many forms such as neurodegenerative diseases, tumors, and stroke. Millions of people currently suffer from neurological diseases worldwide. While Challenges of current diagnosis and... -
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- Effects of Type I Collagen Concentration in Hydrogel on the Growth and Phenotypic Expression of Rat Chondrocytes
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Jin GZ, Kim HW
- KMID: 2394972
- Tissue Eng Regen Med.
- 2017 Aug;14(4):383-391.
- doi: 10.1007/s13770-017-0060-3
It is controversial whether type I collagen itself can maintain and improve chondrogenic phenotype of chondrocytes in a three-dimensional (3D) environment. In this study, we examined the effect of type... -
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- Method-Isolation and Culture of Primary Rat Adipose Derived Stem Cells Using Porous Biopolymer Microcarriers
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Jin GZ, Park JH, Wall I, Kim HW
- KMID: 2361008
- Tissue Eng Regen Med.
- 2016 Jun;13(3):242-250.
- doi: 10.1007/s13770-016-0040-z
Adipose-derived stem cells (ADSCs) are an attractive source of material for mesenchymal stem cell research due to the abundance of adipose and relative ease of access compared with bone marrow.... -
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- Chondrogenic Potential of Dedifferentiated Rat Chondrocytes Reevaluated in Two- and Three-Dimensional Culture Conditions
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Jin GZ, Kim HW
- KMID: 2410511
- Tissue Eng Regen Med.
- 2018 Apr;15(2):163-172.
- doi: 10.1007/s13770-017-0094-6
For the cartilage repair, the cell sources currently adopted are primarily chondrocytes or mesenchymal stem cells (MSCs). Due to the fact that chondrocytes dedifferentiate during 2-dimensional (2D) expansion, MSCs are... -
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- Alginate-Hyaluronic Acid-Collagen Composite Hydrogel Favorable for the Culture of Chondrocytes and Their Phenotype Maintenance
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Mahapatra , Jin GZ, Kim HW
- KMID: 2360802
- Tissue Eng Regen Med.
- 2016 Oct;13(5):538-546.
- doi: 10.1007/s13770-016-0059-1
Articular cartilage has limited regeneration capacity, thus significant challenge has been made to restore the functions. The development of hydrogels that can encapsulate and multiply cells, and then effectively maintain... -
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- Co-culture of Human Dental Pulp Stem Cells and Endothelial Cells Using Porous Biopolymer Microcarriers: A Feasibility Study for Bone Tissue Engineering
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Jin GZ, Kim HW
- KMID: 2394973
- Tissue Eng Regen Med.
- 2017 Aug;14(4):393-401.
- doi: 10.1007/s13770-017-0061-2
Delivery of stem cells with osteogenesis while enabling angiogenesis is important for vascularized bone tissue engineering. Here a three-dimensional (3D) co-culture system of dental pulp stem cells (DPSCs) and endothelial... -
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- Enhanced tyrosine hydroxylase expression in PC12 cells co-cultured with feline mesenchymal stem cells
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Jin GZ, Yin XJ, Yu XF, Cho SJ, Lee HS, Lee HJ, Kong IK
- KMID: 1106218
- J Vet Sci.
- 2007 Dec;8(4):377-382.
- doi: 10.4142/jvs.2007.8.4.377
Mesenchymal stem cells (MSCs) secrete a variety of neuroregulatory molecules, such as nerve growth factor, brain-derived neurotrophic factor, and glial cell-derived neurotrophic factor, which upregulate tyrosine hydroxylase (TH) gene expression... -
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