- FGFR4 Gly388Arg Polymorphism Affects the Progression of Gastric Cancer by Activating STAT3 Pathway to Induce Epithelial to Mesenchymal Transition
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Ye Y, Li J, Jiang D, Li J, Xiao C, Li Y, Han C, Zhao C
- KMID: 2507942
- Cancer Res Treat.
- 2020 Oct;52(4):1162-1177.
- doi: 10.4143/crt.2020.138
Purpose Fibroblast growth factor receptor 4 (FGFR4) plays a critical role in cancer progression involving in tumor proliferation, invasion, and metastasis. This study clarified the role of FGFR4-Arg388 variant in gastric... -
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- Rapamycin Inhibits Transforming Growth Factor beta1-Induced Fibrogenesis in Primary Human Lung Fibroblasts
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Gao Y, Xu X, Ding K, Liang Y, Jiang D, Dai H
- KMID: 1503908
- Yonsei Med J.
- 2013 Mar;54(2):437-444.
- doi: 10.3349/ymj.2013.54.2.437
PURPOSE: The present study was designed to determine whether rapamycin could inhibit transforming growth factor beta1 (TGF-beta1)-induced fibrogenesis in primary lung fibroblasts, and whether the effect of inhibition would occur... -
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- D-RADA16-RGD-Reinforced Nano-Hydroxyapatite/Polyamide 66 Ternary Biomaterial for Bone Formation
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Zhao W, He B, Zhou A, Li Y, Chen X, Yang Q, Chen B, Qiao B, Jiang D
- KMID: 2449248
- Tissue Eng Regen Med.
- 2019 Apr;16(2):177-189.
- doi: 10.1007/s13770-018-0171-5
BACKGROUND: Nano-hydroxyapatite/polyamide 66 (nHA/PA66) is a composite used widely in the repair of bone defects. However, this material is insufficient bioactivity. In contrast, D-RADA16-RGD self-assembling peptide (D-RADA16-RGD sequence containing all... -
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- RhGLP-1 (7–36) protects diabetic rats against cerebral ischemia-reperfusion injury via up-regulating expression of Nrf2/HO-1 and increasing the activities of SOD
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Fang Y, Liu X, Zhao L, Wei Z, Jiang D, Shao H, Zang Y, Xu J, Wang Q, Liu Y, Peng Y, Yin X
- KMID: 2388693
- Korean J Physiol Pharmacol.
- 2017 Sep;21(5):475-485.
- doi: 10.4196/kjpp.2017.21.5.475
The present study aimed to explore the neuroprotective effect and possible mechanisms of rhGLP-1 (7–36) against transient ischemia/reperfusion injuries induced by middle cerebral artery occlusion (MCAO) in type 2 diabetic... -
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