- The Inhibitory Effect of Shikonin on the Agonist-Induced Regulation of Vascular Contractility
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Je HD, Kim HD, La HO
- KMID: 2380332
- Biomol Ther.
- 2015 May;23(3):233-237.
- doi: 10.4062/biomolther.2014.148
Shikonin, a natural flavonoid found in the roots of Lithospermum erythrorhizon, has been shown to possess many biological functions. The present study was undertaken to investigate the influence of shikonin... -
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- The Inhibitory Effect of Eupatilin on the Agonist-Induced Regulation of Vascular Contractility
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Je HD, Kim HD, Jeong JH
- KMID: 1432760
- Korean J Physiol Pharmacol.
- 2013 Feb;17(1):31-36.
- doi: 10.4196/kjpp.2013.17.1.31
The present study was undertaken to investigate the influence of eupatilin on vascular smooth muscle contractility and to determine the mechanism involved. Denuded aortic rings from male rats were used... -
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- The Inhibitory Effect of Apigenin on the Agonist-Induced Regulation of Vascular Contractility via Calcium Desensitization-Related Pathways
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Je HD, Kim HD, La HO
- KMID: 2170648
- Biomol Ther.
- 2014 Mar;22(2):100-105.
Apigenin, a natural flavonoid found in a variety of vegetables and fruits, has been shown to possess many biological functions. The present study was undertaken to investigate the influence of... -
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- Cardamonin inhibits agonist-induced vascular contractility via Rho-kinase and MEK inhibition
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Je HD, Jeong JH
- KMID: 2150475
- Korean J Physiol Pharmacol.
- 2016 Jan;20(1):69-74.
- doi: 10.4196/kjpp.2016.20.1.69
The present study was undertaken to investigate the influence of cardamonin on vascular smooth muscle contractility and to determine the mechanism(s) involved. Denuded aortic rings from male rats were used... -
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- The Effect of Luteolin on the Modulation of Vascular Contractility via ROCK and CPI-17 Inactivation
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Yoon HJ, Kang DH, Jin F, Bang JS, Sohn UD, Je HD
- KMID: 2539588
- Biomol Ther.
- 2023 Mar;31(2):193-199.
- doi: 10.4062/biomolther.2022.087
In this investigation, we made a study of the efficacy of luteolin (a flavonoid found in plants such as vegetables, herbs and fruits) on vascular contractibility and to elucidate the... -
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- Endothelium-Independent Effect of Fisetin on the Agonist-Induced Regulation of Vascular Contractility
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Je HD, Sohn UD, La HO
- KMID: 2170541
- Biomol Ther.
- 2016 Jan;24(1):57-61.
- doi: 10.4062/biomolther.2015.104
Fisetin, a natural flavonoid found in a variety of vegetables and fruits, has been shown to possess many biological functions. The present study was undertaken to investigate the influence of... -
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- The Effect of Galangin on the Regulation of Vascular Contractility via the Holoenzyme Reactivation Suppressing ROCK/CPI-17 rather than PKC/CPI-17
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Yoon HJ, Jung WP, Min YS, Jin F, Bang JS, Sohn UD, Je HD
- KMID: 2526816
- Biomol Ther.
- 2022 Mar;30(2):145-150.
- doi: 10.4062/biomolther.2021.087
In this study, we investigated the influence of galangin on vascular contractibility and to determine the mechanism underlying the relaxation. Isometric contractions of denuded aortic muscles were recorded and combined... -
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- Hypothermia Inhibits Endothelium-Independent Vascular Contractility via Rho-kinase Inhibition
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Chung YH, Oh KW, Kim ST, Park ES, Je HD, Yoon HJ, Sohn UD, Jeong JH, La HO
- KMID: 2429053
- Biomol Ther.
- 2018 Mar;26(2):139-145.
- doi: 10.4062/biomolther.2016.233
The present study was undertaken to investigate the influence of hypothermia on endothelium-independent vascular smooth muscle contractility and to determine the mechanism underlying the relaxation. Denuded aortic rings from male... -
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- The p90rsk-mediated signaling of ethanol-induced cell proliferation in HepG2 cell line
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Kim HS, Kim SJ, Bae J, Wang Y, Park SY, Min YS, Je HD, Sohn UD
- KMID: 2364263
- Korean J Physiol Pharmacol.
- 2016 Nov;20(6):595-603.
- doi: 10.4196/kjpp.2016.20.6.595
Ribosomal S6 kinase is a family of serine/threonine protein kinases involved in the regulation of cell viability. There are two subfamilies of ribosomal s6 kinase, (p90rsk, p70rsk). Especially, p90rsk is... -
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- Endothelium Independent Effect of Pelargonidin on Vasoconstriction in Rat Aorta
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Min YS, Yoon HJ, Je HD, Lee JH, Yoo SS, Shim HS, Lee HY, La HO, Sohn UD
- KMID: 2420388
- Biomol Ther.
- 2018 Jul;26(4):374-379.
- doi: 10.4062/biomolther.2017.197
In this study, we investigated the effects of pelargonidin, an anthocyanidin found in many fruits and vegetables, on endothelium-independent vascular contractility to determine the underlying mechanism of relaxation. Isometric contractions... -
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