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DNA Damage Response Mediated through BRCA1

Jang ER, Lee JS

  • KMID: 2166134
  • Cancer Res Treat.
  • 2004 Aug;36(4):214-221.
The BRCA1 gene was identified and cloned in 1994 based on its linkage to early onset breast and ovarian cancer syndromes in women. The tumor suppressor, BRCA1 is known as...
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ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response

Jang ER, Choi JD, Park MA, Jeong G, Cho H, Lee JS

Chromatin structure has a crucial role in a diversity of physiological processes, including development, differentiation and stress responses, via regulation of transcription, DNA replication and DNA damage repair. Histone deacetylase...
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