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Isotretinoin exposure in pregnant women in Korea

Kim NR, Yoon SR, Choi JS, Ahn HK, Lee SY, Hong DS, Yun JS, Hong SY, Kim YH, Han JY

OBJECTIVE: Isotretinoin is a notorious teratogen otherwise used for the treatment of acne vulgaris. Some countries, including those in North America and the European Union, implemented the pregnancy prevention program...
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A Case of Confluent and Reticulated Papillomatosis Treated with Oral Isotretinoin

Kim H, Park SH, Kim DH, Kang JN, Seol JE, Sung HS

  • KMID: 2383001
  • Korean J Dermatol.
  • 2016 Jun;54(5):397-398.
No abstract available.
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A Case of Acne Fulminans after Oral Isotretinoin Therapy

Ko HS, Moon JH, Kang MJ, Byun JW, Shin J, Choi GS

  • KMID: 2251151
  • Korean J Dermatol.
  • 2016 May;54(4):297-300.
Acne fulminans (AF) is a rare severe form of acne associated with systemic symptoms. It primarily affects male adolescents and is clinically characterized by painful ulcerative nodules on the face,...
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A Case of Cyclosporine-Induced Sebaceous Hyperplasia in a Renal Transplant Patient Successfully Treated with Isotretinoin

Jung HY, Kim M, Cho BK, Park HJ

No abstract available.
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The Effect of Evening Primrose Oil for the Prevention of Xerotic Cheilitis in Acne Patients Being Treated with Isotretinoin: A Pilot Study

Park KY, Ko EJ, Kim IS, Li K, Kim BJ, Seo SJ, Kim MN, Hong CK

BACKGROUND: The most common adverse effects of oral isotretinoin are cheilitis, skin dryness, dry eyes, and conjunctivitis, whereas evening primrose oil (EPO) is known to improve skin moisture and transepidermal...
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Effects of Gamma-Linolenic Acid for the Treatment of Acne Vulgaris Treated with Isotretinoin

Jeong MG, Kim JE, Ahn JY, Ko JY, Park MY, Ro YS

  • KMID: 2146283
  • Korean J Dermatol.
  • 2013 Nov;51(11):863-870.
BACKGROUND: Oral isotretinoin is an effective treatment modality for acne, but this agent may cause dryness of the skin and mucous membrane. Gamma-linolenic acid (GLA) has been known to improve...
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Decreased Hydrogen Peroxide Generation by Neutrophils from Acne Patients Treated with Isotretinoin

Kim WH, Park EJ, Park MW, Cho HS, Kim HJ, Kim CW, Cho HJ, Kim KH, Kim KJ, Kang KR

Background: Reactive oxygen species (ROS) generated by neutrophils are closely correlated with the pathogenesis of a variety of inflammatory skin diseases. The aim of this study was to investigate whether...
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A Case of Generalized Granuloma Annulare Controlled by Isotretinoin

Kim HD, Park CH, Lee SY, Lee JS, Cho MK, Whang KU

  • KMID: 2248933
  • Korean J Dermatol.
  • 2006 Aug;44(8):995-997.
Generalized granuloma annulare (GGA) is an uncommon type of granuloma annulare. It is frequently characterized by chronicity and unresponsiveness to a number of therapeutic modalities. A variety of systemic treatment...
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Comparison of Cost and Effectiveness between Isotretinoin versus Minocycline in the Treatment of Patients with Acne

Yoon YH, Ro BI, Seo SJ, Kim MN, Hong CK

  • KMID: 1931196
  • Korean J Dermatol.
  • 2005 Sep;43(9):1200-1206.
BACKGROUND: Pharmacoeconomic analysis is increasingly becoming an integral component of the overall profile of new drugs. Since its introduction in 1981, isotretinoin (13-cis-retinoic acid) has revolutionized the treatment of severe...
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The Relapse Rate after 1 Year Treatment with Oral Isotretinoin in Korean Patients with Mild to Moderate Acne

Lee JW, Chang SJ, Suh DH, Sung KJ, Lee SH, Choi EH

  • KMID: 2116091
  • Korean J Dermatol.
  • 2004 Jun;42(6):675-681.
BACKGROUND: The efficacy of isotretinoin in the treatment of acne has been widely established. Recently oral isotretinoin has been used for any grades and any types of acne. There have...
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A Case of Generalized Pustular Psoriasis Improved with Isotretinoin

Oh JJ, Park JH, Kim SH, Lee DY, Lee JH, Lee ES

  • KMID: 1977866
  • Korean J Dermatol.
  • 2003 Dec;41(12):1667-1669.
Generalized pustular psoriasis is a lethal variant of psoriasis characterized by the appearance of sterile pustules on psoriatic skin. Etretinate and acitretin are effective in pustular forms of psoriasis, including...
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A Case of Multiple Bowen's Disease Improved with Isotretinoin and Interferon Alpha-2a

Kim JS, Kim HW, Suhr KB, Lee JH, Park JK

  • KMID: 2013671
  • Korean J Dermatol.
  • 2002 May;40(5):592-595.
We report a case of multiple Bowen's disease in a 36-year-old female patient who had multiple erythematous, scaly patches and plaques distributed diffusely on her trunk, upper and lower extremities....
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Radiosensitizing Effect of Administration of 13-cis-Retinoic Acid and Interferon-Alpha-2a in Normal Cervical Keratinocyte and Cervical Cancer Cell Lines

Zin YJ, Kim BG

  • KMID: 1572595
  • Korean J Gynecol Oncol Colposc.
  • 2001 Dec;12(4):310-317.
OBJECTIVE: This study was performed to evaluate the radiosensitizing effect of combined administration of 13-cis-retinoic acid (cRA) and interferon-alpha-2a (INF) in normal cervical keratinocyte and cervical cancer cell lines. METHODS: cRA,...
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A Case of Acne Fulminans Treated with Oral Isotretinoin and Systemic Corticosteroid

Kim KJ, Kim ES, Choi JH, Sung KJ, Moon KC, Koh JK

  • KMID: 2250996
  • Korean J Dermatol.
  • 2001 Nov;39(11):1337-1339.
Acne fulminans is a rare, severe and destructive disease with the acute onset of painful, nodulocystic, ulcerative, acneiform lesions and frequently associated with systemic signs and symptoms including fever, weight...
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The Efficacy and Safety of Isotretinoin in Korean Patients with Mild to Moderate Acne

Choi EH, Hwang SM, Suh DH, Sung KJ, Lee SH

  • KMID: 1568840
  • Korean J Dermatol.
  • 2000 Oct;38(10):1309-1314.
BACKGROUND: Oral isotretinoin has been widely used in severe acne patients and is known as a very effective drug. Recently it is being used in any grades and any types...
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Recurrence of Acne after Oral Isotretinoin

Chang SE, Park IJ, Choi JH, Sung KJ, Moon KC, Koh JK

BACKGROUND: The clinical efficacy of oral isotretinoin in the treatment of severe acne is well established but there is no published data about the recurrence rate and the optimum dose...
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A Case of Darier's Disease Improved with Oral Etretinate and Isotretinoin, and CO2 Laser Vaporization

Jung MJ, Lee SJ, Cho YW, Han JY, Song KY

  • KMID: 2303378
  • Korean J Dermatol.
  • 1999 Jun;37(6):775-780.
We report a case of Darier's disease with typical cutaneous and nail lesions in a 50-year-old male patient. He has brownish hyperkeratotic papules on the ant.chest, back, both axilla and...
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Perifolliculitis Capitis Abscedens et Suffodiens Successfully Treated with Isotretinoin

Jeon HD, Oh KS, Lee SY, Lee JS, Whang KU

  • KMID: 1548115
  • Korean J Dermatol.
  • 1999 Mar;37(3):386-389.
Perifolliculitis capitis abscedens et suffodiens is a rare chronic recalcitrant follicular disorder which clinically presents itself as pulstules, nodules, intercommunicating abscess and sinuses that leave atrophic, hypertrophic or keloidal scars....
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The Effect of All-trans and 13-cis-retinoic Acid in Medulloblastoma and Glioblastoma Cell Culture

Yoon SH, Kim SH, Ahn YH, Ahn YM, Cho KH, Cho KG, Kim SH

  • KMID: 2177119
  • J Korean Child Neurol Soc.
  • 1998 May;5(2):217-227.
PURPOSE: It has been reported that retinoic acid, one of the most popular agents for chemoprevention could inhibit the proliferation of many cancer cells including neuroblastoma and glioblastoma. However, there...
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Interferon-alpha2a, 13-cis-retinoic Acid and Radiotherapy for Locally Advanced Squamous Carcinoma of the uterine Cervix: Preliminary Study

Lee JP, Park TK, Kim SN

  • KMID: 1675657
  • Korean J Gynecol Oncol Colposc.
  • 1995 Sep;6(3):174-182.
Locally advanced cancer of the uterine cervix is a major cause of death worldwide. Standard treatment with rdiolherepy for locally advanced cancer of the uterine cnvix has a response rate...
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