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Pesticide metabolite and oxidative stress in male farmers exposed to pesticide

Lee KM, Park SY, Lee K, Oh SS, Ko SB

BACKGROUND: The objective of this study was to measure malondialdehyde (MDA) and isoprostane which has been used as an index of lipid injury, 8-hydroxy-2′-deoxyguanosine (8-OHdG), which has been used as...
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Eicosanoid Mediators in the Airway Inflammation of Asthmatic Patients: What is New?

Sanak M

Lipid mediators contribute to inflammation providing both pro-inflammatory signals and terminating the inflammatory process by activation of macrophages. Among the most significant biologically lipid mediators, these are produced by free-radical...
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Oxidatvive Stress in Rat Model of Preeclampsia and Clinical Correlates

Chang YJ, Lee WK, Kim HG

  • KMID: 2285336
  • Korean J Physiol Pharmacol.
  • 2007 Jun;11(3):129-133.
There are growing evidences suggesting a pivotal role of oxidative stress in the pathophysiology of preeclampsia. We investigated oxidative stress in the rat model of preeclampsia, and in clinical cases....
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Umbilical Cord Arterial Concentrations of Isoprostane(8-iso-PGF2alpha) in Newborn Infants

Lee KS, Ji YH, Chang YP

  • KMID: 1607029
  • J Korean Pediatr Soc.
  • 2003 Sep;46(9):865-870.
PURPOSE: We measured the umbilical cord arterial concentrations of isoprostane(8-iso-PGF2alpha) and intended to decide whether the umbilical cord arterial concentrations of isoprostane could be used as a useful parameter for...
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Changes in the Levels of Eicosanoids and Isoprostane (8-iso-PGF2alpha) in the Newborn Rat Brain after Hypoxic-Ischemic Injury

Lee HY, Jung MK, Kim JA, Chang YP, Hyun KS, Kim HG, Hwang TJ

  • KMID: 2099016
  • J Korean Soc Neonatol.
  • 2000 May;7(1):45-53.
PURPOSE: The changes in the levels of eicosanoids and isoprostane (8-iso-PGF2alpha) were investigated in brain tissue of 7 day-old rats after hypoxic-ischemic (HI) injury. METHODS: The 7 day-old newborn rats...
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Simultaneous HPLC analysis of arachidonic acid metabolites in biological samples with simple solid phase extraction

Kim HG, Huh YN, Park KS

  • KMID: 2071837
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):779-786.
A reversed-phase high-performance liquid chromatography (RP-HPLC) has been developed to analyze the metabolites of arachidonic acid based on the specificities of ultraviolet absorption of these various metabolites and is sensitive to the nanogram...
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