- Islet Transplantation and Regeneration for Treatment of Diabetes
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Yamada Y
- KMID: 1726146
- Yonsei Med J.
- 2004 Jun;45(Suppl):S53-S55.
- doi: 10.3349/ymj.2004.45.Suppl.53
Islet transplantation has the potential to restore normoglycemia and prevent the development of diabetic complications such as retinopathy, nephropathy and neuropathy, and could therefore ve a valuable treatment for diabetic... -
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- Encapsulated Islet Transplantation: Strategies and Clinical Trials
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Buder B, Alexander , Krishnan R, Chapman DW, Lakey JR
- KMID: 2150783
- Immune Netw.
- 2013 Dec;13(6):235-239.
- doi: 10.4110/in.2013.13.6.235
Encapsulation of tissue has been an area of intense research with a myriad number of therapeutic applications as diverse as cancer, tissue regeneration, and diabetes. In the case of diabetes,... -
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- Islet transplantation
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Son HY
- KMID: 1700051
- J Korean Diabetes Assoc.
- 1993 Jun;17(2):125-134.
No abstract available. -
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- History, current status and perspective of islet transplantation
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Kim JH, Kim KW
- KMID: 2258776
- Korean J Med.
- 2008 Sep;75(3):274-279.
Islet transplantation has been considered as an attractive procedure due to its simplicity, and because it can improve glycemic control in type 1 diabetic patient with hypoglycemic unawareness. In 2000,... -
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- Is islet transplantation a realistic approach to curing diabetes?
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Jin SM, Kim KW
- KMID: 2365978
- Korean J Intern Med.
- 2017 Jan;32(1):62-66.
- doi: 10.3904/kjim.2016.224
Since the report of type 1 diabetes reversal in seven consecutive patients by the Edmonton protocol in 2000, pancreatic islet transplantation has been reappraised based on accumulated clinical evidence. Although... -
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- Insight into Microenvironment Remodeling in Pancreatic Endocrine Tissue Engineering: Biological and Biomaterial Approaches
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Kaviani M, Azarpira N
- KMID: 2360796
- Tissue Eng Regen Med.
- 2016 Oct;13(5):475-484.
- doi: 10.1007/10.1007/s13770-016-0014-1
The treatment of diabetes mellitus, as a chronic and complicated disease, is a valuable purpose. Islet transplantation can provide metabolic stability and insulin independence in type 1 diabetes patients. Diet... -
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- Pancreas Islet Transplantation
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Cha BY, Son HS
- KMID: 2177904
- J Korean Diabetes Assoc.
- 2000 Apr;24(2):165-169.
No abstract available. -
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- Cell Replacement and Regeneration Therapy for Diabetes
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Jun HS
- KMID: 2222380
- Korean Diabetes J.
- 2010 Apr;34(2):77-83.
- doi: 10.4093/kdj.2010.34.2.77
Reduction of beta cell function and a beta cell mass is observed in both type 1 and type 2 diabetes. Therefore, restoration of this deficiency might be a therapeutic option... -
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- Human Islet Transplantation
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Ahn YB
- KMID: 2008135
- J Korean Diabetes Assoc.
- 2004 Feb;28(1):1-8.
No abstract available. -
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- Transplantation of Langerhans islet into digestive organs of the diabetic rat
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Kim BM, Min BH, Park IS
- KMID: 1530637
- Korean J Anat.
- 1999 Dec;32(6):869-881.
Although replacement therapy with insulin can prevent acute metabolic disorder in patients with IDDM (insulin dependent diabetes mellitus), it does not permanently restore glucose homeostasis. Recently it has been reported... -
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- Experimental Pancreas Islet Isolation in Non- Human Primate
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Kim SC, Han DJ, Hering BJ
- KMID: 2198970
- J Korean Soc Transplant.
- 2001 Dec;15(2):142-146.
Transplantation of the pancreas islet cell has been demonstrated to be able to cure for type I diabetes. It can offer not only discontinuing of insulin but also preventing of... -
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- Study for the Improvement of Early Implantation and Long Term Graft Survival in Pancreatic Islet Cell Transplantation by Induction of Angiogenesis with Gene Transfection of Vascuar Endothelial Growth Factor
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Kim SC, Kim TH, We YM, Park HY, Cho KM, Han DJ
- KMID: 2003710
- J Korean Soc Transplant.
- 2000 Jun;14(1):47-58.
PURPOSE: Transplantation of pancreas islet has been worldwidely studied as a one of therapeutic modalities to achieve the insulin independence. We studied whether the expression of vascular endothelial growth factor... -
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- Immune Tolerance in Murine Islet Transplantation Across HY Disparity
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Choi SE, Park CG
- KMID: 2054244
- Immune Netw.
- 2004 Mar;4(1):53-59.
- doi: 10.4110/in.2004.4.1.53
BACKGROUND: Minor histocompatibility HY antigen, as a transplantation antigen, has been known to cause graft rejection in MHC (major histocompatibility complex) matched donor-recipient. The aim of our study is to... -
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- Pancreatic Islets Transplantation through Spleenic Pulp and Peritoneum Using Hollow Fiber in Streptozotocin-induced Diabetic Nude Mouse
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Park H, Kim JB, Kim ER, Cho HP, Kim IS
- KMID: 2193690
- J Korean Soc Pediatr Endocrinol.
- 2000 Jun;5(1):107-114.
PURPOSE: Recently islets transplantation has been become a hot issue in insulin dependant diabetes mellitus. This study is aimed to review the technical method of islet isolation, pruification, and microencapsulation... -
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- Transplantation of betacellulin-transduced islets improves glucose intolerance in diabetic mice
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Song MY, Bae UJ, Jang KY, Park BH
- KMID: 2155363
- Exp Mol Med.
- 2014 May;46(5):e98.
- doi: 10.1038/emm.2014.24
Type 1 diabetes is an autoimmune disease caused by permanent destruction of insulin-producing pancreatic beta cells and requires lifelong exogenous insulin therapy. Recently, islet transplantation has been developed, and although... -
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- Effect of nicotinamide on early graft failure following intraportal islet transplantation
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Jung DY, Park JB, Joo SY, Joh JW, Kwon CH, Kwon GY, Kim SJ
- KMID: 1122279
- Exp Mol Med.
- 2009 Nov;41(11):782-792.
- doi: 10.3858/emm.2009.41.11.084
Intraportal islet transplantation (IPIT) may potentially cure Type 1 diabetes mellitus; however, graft failure in the early post-transplantation period presents a major obstacle. In this study, we tested the ability... -
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- Experimental Study on Cryopreservation of Pancreas Islet Cell in Rat
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Back JH, Kim SC, Kim IH, We YM, Kim YH, Kim JH, Cho IH, Cho EY, Lim DG, Han DJ
- KMID: 2201805
- J Korean Soc Transplant.
- 2005 Dec;19(2):124-130.
PURPOSE: Cryopreservation of pancreas islet cells can facilitate the clinical islet transplantation by giving a means of storage of islets and immunomodulation on pancreatic islet preparations. METHODS: Pancreatic islets were isolated... -
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- Alginate-Catechol Cross-Linking Interferes with Insulin Secretion Capacity in Isolated Murine Islet Cells
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Kim YS, Cho SW, Ko B, Shin J, Ahn CW
- KMID: 2418709
- Diabetes Metab J.
- 2018 Apr;42(2):164-168.
- doi: 10.4093/dmj.2018.42.2.164
Over the past three decades, human pancreatic islet isolation and transplantation techniques have developed as a routine clinical procedure for selected patients with type 1 diabetes mellitus. However, due to... -
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- Islet Encapsulation Using Chondrocyte
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Lee JI, Kim JY, Lee JG, Kim YS
- KMID: 1941312
- J Korean Soc Transplant.
- 2014 Dec;28(4):187-194.
- doi: 10.4285/jkstn.2014.28.4.187
Diabetes mellitus is one of the leading metabolic diseases that cause an increasing rate of mortality and morbidity. Recently, rather than the current drug treatment, pancreatic islet transplantation has been... -
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- Stepwise Approach to Problematic Hypoglycemia in Korea: Educational, Technological, and Transplant Interventions
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Jin SM
- KMID: 2384077
- Endocrinol Metab.
- 2017 Jun;32(2):190-194.
- doi: 10.3803/EnM.2017.32.2.190
Impaired awareness of hypoglycemia has been found to be prevalent in 20% to 40% of people with type 1 diabetes. If a similar prevalence exists in Koreans with type 1... -
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