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Effects of Halothane and Fentanyl Anesthesia on Coronary Endothelial Endothelin-1 Production During Myocardial Ischemia-Reperfusion in Dogs

Kim KS, Rhee GY, Yoo KY, Ha IH

Endothelin(ET), is the most potent endogenous vasoconstrictor. Myocardial ischemia and chemical stimuli including calcium ionophores are known to release ET-1. Recently, halothane has been shown to block calcium channel. Thus,...
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A Study of Epidermal Apoptosis

Park YL, Whang KU, Park JH

  • KMID: 2086019
  • Korean J Dermatol.
  • 1998 Feb;36(1):59-70.
BACKGROUND: Apoptosis is a highly selective form of cell suicide with characteristic morphologieal and biochemical features, including chromatin condensation, formation of apoptotic bodies, and DNA fragmentation by the activation of...
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Requirements for in vitro growth of human thymocytes

Park SH, Bae YM, Park WS, Kim TJ, Chung DH, Song HG, Cho BJ, Kim CW, Lee SK

Since it is difficult to study human thymocyte maturation in vitro, we have developed an in vitro thymocyte culture system which has allowed us to select the optimal growth conditions...
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[Na+]i, [K+]i and [Cl-]i regulation of exocytosis in guinea-pig antral mucous cells

Nakahari T, Fujiwara S, Shimamoto

Effects of intracellular Na+, K+ and Cl- on Ca(2+)-regulated exocytosis activated by 10 microM acetylcholine (ACh) were studied in guinea-pig antral mucous cells which are permeabilized by nystatin treatment. Ca(2+)-regulated...
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Involvement of throm box aneA2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation

Rasheed H, Saeed SA

  • KMID: 1097103
  • Exp Mol Med.
  • 2004 Jun;36(3):220-225.
The present study was carried out to examine the mechanisms of the synergistic interaction of PAF and A23187 mediated platelet aggregation. We found that platelet aggregation mediated by subthreshold concentrations...
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Comparison of basophil histamine releasability between atopic and nonatopic thmatics

Son JW, Kim YK, Chung JW, Lee SR, Cho SH, Min KU, Koh YY, Kim YY

To compare the mediator releasability between atopic and nonatopic asthmatics, we measured basophil histamine releasability (BaHR) using a calcium-ionophore A23187 and anti-IgE in 137 subjects who were treated at Seoul...
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Influence of calcium ion on host cell invasion and intracellular replication by Toxoplasma gondii

Song HO, Ahn MH, Ryu JS, Min DY, Joo KH, Lee YH

Toxoplasma gondii is an obligate intracellular protozoan parasite, which invades a wide range of hosts including humans. The exact mechanisms involved in its invasion are not fully understood. This study...
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Swelling of the vesicle is prerequisite for PTH secretion

Lim SK, Kwon YH, Song YD, Lee HC, Ryu KJ, Huh KB, Park CS

Unlike most secretory cells, high extra cellular calcium inhibits rather than stimulates hormonal secretion in several cells such as parathyroid cells, Juxtaglomerular cells and osteoclast. To gain further insight into...
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Calcium-influx increases SOD1 aggregates via nitric oxide in cultured motor neurons

Kim HJ, Im W, Kim S, Kim SH, Sung JJ, Kim M, Lee KW

  • KMID: 1090960
  • Exp Mol Med.
  • 2007 Oct;39(5):574-582.
Familial amyotrophic lateral sclerosis (fALS) is caused by mutations in Cu/Zn-superoxide dismutase (SOD1), and SOD1 aggregation and calcium toxicity are involved in neuronal death. However, the effect of altered calcium...
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Transglutaminase 2 inhibits apoptosis induced by calciumoverload through down-regulation of Bax

Cho SY, Lee JH, Bae HD, Jeong EM, Jang GY, Kim CW, Shin DM, Jeon JH, Kim IG

An abrupt increase of intracellular Ca2+ is observed in cells under hypoxic or oxidatively stressed conditions. The dysregulated increase of cytosolic Ca2+ triggers apoptotic cell death through mitochondrial swelling and...
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