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Secretagogin deficiency causes abnormal extracellular trap formation in microglia

Kim YG, Kim DY

Extracellular traps (ETs), primarily composed of DNA and antibacterial peptides, are mainly secreted by neutrophils to inhibit pathogen spread and eliminate microorganisms. Recent reports suggest that microglia can also secrete...
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Antitumor effects of ophiopogonin D on oral squamous cell carcinoma

Trang NTK, Dong VP, Yoo H

Ophiopogonin D (OPD) is a steroidal glycoside derived from Ophiopogon japonicus, a traditional Chinese medicine with diverse biological activities, including antithrombosis, anti-inflammation, and antitussive effects. To investigate the cellular effects...
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Study on histological features and Bmp4 expression pattern during tooth formation and replacement in Xenopus laevis

Lee YH, Guo R, Li Y, Park BK

This study explores the histological features and Bmp4 expression patterns in the replaced tooth germ of Xenopus laevis. Tooth germ formation starts from the dental placode through epithelial-mesenchymal interactions, involving...
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Mechanisms underlying diabetes-induced bone loss

Song JH, Piao X, Koh JT

Diabetes, a chronic hyperglycemic condition, is caused by insufficient insulin secretion or functional impairment. Long-term inadequate regulation of blood glucose levels or hyperglycemia can lead to various complications, such as retinopathy,...
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