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Genome-based identification of strain KCOM 1265 isolated from subgingival plaque at the species level

Park SN, Lim YK, Kook JK

The aim of this study was to identify strain KCOM 1265 isolated from subgingival plaque at the species level by comparing 16S ribosomal RNA gene (16S rDNA) and genome sequences....
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Short-chain fatty acids, including acetate, propionate, and butyrate, elicit differential regulation of intracellular Ca2+ mobilization, expression of IL-6 and IL-8, and cell viability in gingival fibroblast cells

Kim SH, Kim MS

Short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate are secondary metabolites produced by anaerobic fermentation of dietary fibers in the intestine. Intestinal SCFAs exert various beneficial effects on...
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Homer2 regulates amylase secretion via physiological calcium oscillations in mouse parotid gland acinar cells

Kang N, Kang JY, Shin DM, Yang YM

The salivary glands secrete saliva, which plays a role in the maintenance of a healthy oral environment. Under physiological conditions, saliva secretion within the acinar cells of the gland is...
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Change in fibrinogen levels and severe postoperative bleeding in cardiac surgery

Kim EJ, Kim JY, Kim HY, Hwang BY, Cho AR, Jung YH, Baek SH, Hong JM

Thromboelastography or rotational thromboelastometry, is being increasingly utilized in cardiac surgery of late. However, it is an indirect test and is not available in all centers. Low fibrinogen levels before...
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The role of lysophosphatidic acid receptor 1 in inflammatory response induced by lipopolysaccharide from Porphyromonas gingivalis in human periodontal ligament stem cells

Kim DH, Seo EJ, Tigyi GJ, Lee BJ, Jang IH

Lysophosphatidic acid (LPA) is a lipid messenger mediated by G protein-coupled receptors (LPAR1-6). It is involved in the pathogenesis of certain chronic inflammatory and autoimmune diseases. In addition, it controls...
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Flavonoids as anti-inflammatory and neuroprotective agents

Lee H, Selvaraj B, Yoo KY, Ko SH

Neuroinflammation is known as the main mechanism implicated in the advancement of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. The main feature of neuroinflammation is associated with the...
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