- Effect of Metformin on Cell Growth and Differentiation in Cultured Odontoblasts
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Oh CY, Kim SG, Go DS, Yu SK, Kim TH, Kim CS, Park JC, Kim DK
- KMID: 2385804
- Int J Oral Biol.
- 2017 Jun;42(2):39-45.
- doi: 10.11620/IJOB.2017.42.2.039
Metformin (1,1-dimethylbiguanide hydrochloride), derived from French lilac (Galega officinalis), is a first-line anti-diabetic drug prescribed for patients with type 2 diabetes. However, the role of metformin in odontoblastic cell differentiation... -
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- Association between 14bp Insertion/Deletion Polymorphism in Exon 8 of HLA-G gene and Oral Squamous Cell Carcinoma in Korean Population
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Kang SW, Ban JY
- KMID: 2385809
- Int J Oral Biol.
- 2017 Jun;42(2):79-83.
- doi: 10.11620/IJOB.2017.42.2.079
Abnormal HLA-G expression occurs in various diseases such as melanoma, renal cell carcinoma, asthma, and classic Hodgkin's lymphoma. The purpose of this study was to determine whether HLA-G gene is... -
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- Water Extracts of Anthriscus sylvestris Leaf induces Apoptosis in FaDu Human Hypopharynx Squamous Carcinoma Cells
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Yang JE, Lee SA, Moon SM, Han SH, Choi YH, Kim SG, Kim DK, Park BR, Kim CS
- KMID: 2385805
- Int J Oral Biol.
- 2017 Jun;42(2):47-54.
- doi: 10.11620/IJOB.2017.42.2.047
Anthriscus sylvestris (L.) Hoffm. is a perennial herb found widely distributed in various regions of Korea, Europe, and New Zealand. The root of A. sylvestris have been extensively used in... -
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- Development of Refolding Process to Obtain Active Recombinant Human Bone Morphogenetic Protein-2 and its Osteogenic Efficacy on Oral Stem Cells
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Lee JH, Jang YJ
- KMID: 2385808
- Int J Oral Biol.
- 2017 Jun;42(2):71-78.
- doi: 10.11620/IJOB.2017.42.2.071
BMP-2 is a well-known TGF-beta related growth factor, having a significant role in bone and cartilage formation. It has been employed to promote bone formation in some clinical trials, and... -
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- Development of a Novel Subunit Vaccine Targeting Fusobacterium nucleatum FomA Porin Based on In Silico Analysis
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Jeong K, Sao P, Park MJ, Lee H, Kim SH, Rhee JH, Lee SE
- KMID: 2385807
- Int J Oral Biol.
- 2017 Jun;42(2):63-70.
- doi: 10.11620/IJOB.2017.42.2.063
Selecting an appropriate antigen with optimal immunogenicity and physicochemical properties is a pivotal factor to develop a protein based subunit vaccine. Despite rapid progress in modern molecular cloning and recombinant... -
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- Action of Mitochondrial Substrates on Neuronal Excitability in Rat Substantia Gelatinosa Neurons
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Lee HI, Chun SW
- KMID: 2385806
- Int J Oral Biol.
- 2017 Jun;42(2):55-61.
- doi: 10.11620/IJOB.2017.42.2.055
Recent studies indicate that mitochondria are an important source of reactive oxygen species (ROS) in the spinal dorsal horn. In our previous study, application of malate, a mitochondrial electron transport... -
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