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Effect of hypoxia on angiogenesis-related proteins in human dental pulp cells

Kim MK, Kim SJ, Kim Y, Park HJ, Jo MJ, Bae SK, Kim HJ, Bae MK

Dental pulp is a highly vascularized tissue with high regenerative potential. Revascularization of severed vasculature in the tooth is required for pulp healing during avulsed tooth treatment. In this study,...
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Development of Quantitative Real-Time PCR Primers for Detection of Streptococcus sobrinus

Park SN, Kook JK

The purpose of this study was to develop Streptococcus sobrinus-specific qPCR primers based on the nucleotide sequence of the RNA polymerase β-subunit gene (rpoB). The specificity of the primers was...
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Effects of Reactive Oxygen Species and Nitrogen Species on the Excitability of Spinal Substantia Gelatinosa Neurons

Park JY, Park A, Chun SW

Reactive oxygen species (ROS) and nitrogen species (RNS) are both important signaling molecules involved in pain transmission in the dorsal horn of the spinal cord. Xanthine oxidase (XO) is a...
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Quantitative Ultrastructural Analysis of Endings Presynaptic to the Tooth Pulp Afferent Terminals in the Trigeminal Oral Nucleus

Lee SK, Kim TH, Lee CH, Park SK, Bae YC

The ultrastructural parameters related to synaptic release of endings which are presynaptic to tooth pulp afferent terminals (p-endings) were analyzed to understand the underlying mechanism for presynaptic modulation of tooth...
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Participation of IL-1β in temporomandibular nociception in rats with CFA-induced inflammation

Ju JS, Choi SH, Kim HJ, Son JY, Ahn DK

The aim of the present study was to develop an animal model for evaluation of temporomandibular (TMJ) nociception under TMJ inflammation. We also investigated the participation of IL-1β in inflammation-induced...
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Activation of acetylcholine receptor elicits intracellular Ca2+ mobilization, transient cytotoxicity, and induction of RANKL expression

Heo SJ, Kim MS

Acetylcholine receptors (AChR) including muscarinic and nicotinic AChR are widely expressed and mediate a variety of physiological cellular responses in neuronal and non-neuronal cells. Notably, a functional cholinergic system exists...
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Cellular Effects of Troglitazone on YD15 Tongue Carcinoma Cells

Ta Thi L, Yoo H

An FDA approved drug for the treatment of type II diabetes, Troglitazone (TRO), a peroxisome proliferator–activated receptor gamma agonist, is withdrawn due to severe idiosyncratic hepatotoxicity. In the search for...
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Effect of β-carotene on Cell Growth Inhibition of KB Human Oral Cancer Cells

Yang SS, Kim SG, Park BS, Go DS, Yu SK, Kim CS, Kim J, Kim DK

β-carotene is present in carrots, pumpkins, and sweet potatoes. It suppresses many types of cancers by regulating cellular proliferation and apoptosis through a variety of mechanisms. However, the effects of...
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