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Fast temporal detection of intracellular hydrogen peroxide by HyPer

Yang YM, Lee SJ, Shin DM

  • KMID: 1709611
  • Int J Oral Biol.
  • 2013 Dec;38(4):169-173.
HyPer is the genetically encoded biosensor of intracellular hydrogen peroxide (H2O2), the most stable of the reactive oxygen species (ROS) generated by living cells. HyPer has a high sensitivity and...
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Antimicrobial Activity of Berberine against Oral Bacteria Related to Endodontic Infections

Lee D, Kim MJ, Park SN, Lim YK, Min JB, Hwang HK, Kook JK

  • KMID: 1709607
  • Int J Oral Biol.
  • 2013 Dec;38(4):141-147.
It has been established that berberine has strong antimicrobial effects. Little is known however regarding the antimicrobial activity of berberine against endodontic pathogenic bacteria or its cytotoxicity in human oral...
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Oral Microbiota Comparison between Healthy volunteers, Periodontitis patients and Oral cancer patients

Na HS, Kim S, Choi YH, Lee JY, Chung J

  • KMID: 1709613
  • Int J Oral Biol.
  • 2013 Dec;38(4):181-188.
The presence of distinct bacterial species is found to be dependent on age, diet, and disease. We compared the detection rate of several oral bacterial strains in a cohort of...
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Effect of Xylitol on various Oral bacteria

Na HS, Kim SM, Kim S, Choi YH, Chung J

  • KMID: 1709612
  • Int J Oral Biol.
  • 2013 Dec;38(4):175-180.
Xylitol is a five-carbon sugar alcohol that reduces the incidence of caries by inhibiting the growth of oral streptococci, including Streptococcus mutans. Since xylitol is transported via the fructose phosphotransferase...
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Antimicrobial Activity of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Periodontopathogens

Park SN, Kook JK

  • KMID: 1709608
  • Int J Oral Biol.
  • 2013 Dec;38(4):149-154.
In general, oleanolic acid (OA) and ursolic acid (UA) have antimicrobial effect against Gram-positive bacteria but not Gram-negative bacteria whereas sophoraflavanone G has antimicrobial activity against both bacterial types. However,...
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Cholesterol conjugated spermine as a delivery modality of antisense oligonucleotide

Im YK, Kim MS, Yoo H

  • KMID: 1709609
  • Int J Oral Biol.
  • 2013 Dec;38(4):155-160.
The major issue in the development of nucleic acid based therapeutics is the inefficient delivery of these agents into cells. We prepared cholesterol conjugated spermine and evaluated its usefulness as...
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High dose of QX-314 produces anti-nociceptive effect without capsaicin in rats with inflammatory TMJ pain

Yang KY, Kim MS, Kim EK, Kong MS, Ahn JS, Lee JH, Ju JS, Ahn DK

  • KMID: 1709606
  • Int J Oral Biol.
  • 2013 Dec;38(4):135-140.
The present study investigated the effects of QX-314 on inflammatory pain of the temporomandibular joint (TMJ). Experiments were carried out on male Sprague-Dawley rats weighing 220-280 g. Under anesthesia, the...
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Effects of nanoscale ridge/groovepattern arrayed surface on in vitro differentiation of multi-potent pulp cells derived from human supernumerary teeth

Kim D, Jo H, Lee J, Kim K, Roh S

  • KMID: 1709610
  • Int J Oral Biol.
  • 2013 Dec;38(4):161-167.
Human dental pulp stem cells (DPSCs) are multi-potent mesenchymal stem cells that have several differentiation potentials. An understanding of the tissues that differentiate from these cells can provide insights for...
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