- Association between interleukin 6 promoter variants and chronic hepatitis B progression
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Park BL, Lee HS, Kim YJ, Kim JY, Jung JH, Kim LH, Shin HD
- KMID: 1097254
- Exp Mol Med.
- 2003 Apr;35(2):76-82.
Interleukin 6 (IL6) plays an essential role in the regulation of immune response to chronic disease. In this study, the three known single nucleotide polymorphisms (SNPs) in the IL6 promoter... -
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- Interleukin-6 Receptor Polymorphisms Contribute to the Neurological Status of Korean Patients with Ischemic Stroke
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Kim DH, Yoo SD, Chon J, Yun DH, Kim HS, Park HJ, Kim SK, Chung JH, Kang JK, Lee SA
- KMID: 2363505
- J Korean Med Sci.
- 2016 Mar;31(3):430-434.
- doi: 10.3346/jkms.2016.31.3.430
To investigate the contribution of the interleukin-6 receptor (IL-6R) gene single nucleotide polymorphisms (SNPs) to the neurological status of Korean patients with ischemic stroke (IS), two SNPs of the IL-6R... -
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- IL-10 Polymorphisms and Tuberculosis Susceptibility: An Updated Meta-Analysis
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Ke Z, Yuan L, Ma J, Zhang X, Guo Y, Xiong H
- KMID: 2163619
- Yonsei Med J.
- 2015 Sep;56(5):1274-1287.
- doi: 10.3349/ymj.2015.56.5.1274
PURPOSE: The association of interleukin-10 (IL-10) polymorphisms (-1082G/A, -819C/T, -592A/C) and interleukin-6 (IL-6) poly-morphisms (-174G/C) with tuberculosis (TB) risk has been widely reported. However, the results are controversial. To clarify... -
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- miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes
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Makki MS, Haqqi TM
- KMID: 2160620
- Exp Mol Med.
- 2015 Oct;47(10):e189.
- doi: 10.1038/emm.2015.66
IL-6 is an inflammatory cytokine and its overexpression plays an important role in osteoarthritis (OA) pathogenesis. Expression of IL-6 is regulated post-transcriptionally by MCPIP1. The 3' untranslated region (UTR) of... -
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- Granulocyte Macrophage Colony-Stimulating Factor May Modulate the Post-transcription Pathway of Interleukin-6 Expression in Prostate Carcinoma Cells
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Kim TH, Oh SY, Kim YS, Lee MK, Kim HS, Myung SC
- KMID: 1786852
- J Korean Med Sci.
- 2008 Feb;23(1):94-97.
- doi: 10.3346/jkms.2008.23.1.94
Interleukin-6 (IL-6) can stimulate a variety of tumors including prostatic carcinoma. Research has recently shown that IL-6 may act to stimulate the progression of prostatic cancer. To date, little research... -
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- miR-98 suppresses melanoma metastasis through a negative feedback loop with its target gene IL-6
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Li F, Li XJ, Qiao L, Shi F, Liu W, Li Y, Dang YP, Gu WJ, Wang XG, Liu W
- KMID: 2155381
- Exp Mol Med.
- 2014 Oct;46(10):e116.
- doi: 10.1038/emm.2014.63
Dysregulated microRNA (miRNA) expression has a critical role in tumor development and metastasis. However, the mechanism by which miRNAs control melanoma metastasis is unknown. Here, we report reduced miR-98 expression... -
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