- Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits
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Chen B, Qin J, Wang H, Magdalou J, Chen L
- KMID: 964663
- Exp Mol Med.
- 2010 Oct;42(10):684-695.
- doi: 10.3858/emm.2010.42.10.067
The study investigated the effects of adenovirus-mediated gene transfection of basic fibroblast growth factor (bFGF), bFGF combined with interleukin-1 receptor antagonist protein (IL-Ra) and/or insulin-like growth factor-1 (IGF-1) both in... -
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- Upregulation of Proinflammatory Cytokines in the Fetal Brain of the Gaucher Mouse
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Hong YB, Kim EY, Jung SC
- KMID: 2157830
- J Korean Med Sci.
- 2006 Aug;21(4):733-738.
- doi: 10.3346/jkms.2006.21.4.733
Gaucher disease is caused by a deficiency of glucocerebrosidase. Patients with Gaucher disease are divided into three major phenotypes: chronic nonneuronopathic, acute neuronopathic, and chronic neuronopathic, based on symptoms of... -
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- Age-related regional difference of interleukin-1 expression in rat brain after lipopolysaccharide treatment
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Huh GY, Roh MS, Bae HR
- KMID: 1066502
- J Korean Med Sci.
- 2001 Feb;16(1):103-107.
- doi: 10.3346/jkms.2001.16.1.103
Aging is associated with altered immune responses including dysregulation of cytokine production. Of cytokines, interleukin-1 (IL-1) family has been primarily involved with central nervous system. To evaluate the age-related different... -
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- Protein kinase A mediates microglial activation induced by plasminogen and gangliosides
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Min KJ, Yang MS, Jou I, Joe EH
- KMID: 1123767
- Exp Mol Med.
- 2004 Oct;36(5):461-467.
In the injured brain, microglia is known to be activated and produce proinflammatory mediators such as interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and inducible nitric oxide synthase (iNOS). We investigated... -
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