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Changes of splenocyte IFN-gamma mRNA synthesis in rats infected with Paragonimus westermani

Cho JK, Kwon HS, Joo KH, Lee JS, Cho SW

Changes in the expression level of splenocyte IFN-gamma mRNA of Sprague-Dawley (SD) rats infected with Paragonimus westermani were analyzed by competitive reverse transcription-polymerase chain reaction (RT-PCR) followed by southern...
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Monophosphoryl lipid A (MPL) upregulates major histocompatibility complex (MHC) class I expression by increasing interferon-gamma (IFN-gamma)

Cho CH, Lee BK, Kwak SM, Kim JD

Tumor immunity is primarily mediated by cells as CD8+ cytotoxic T lymphocytes (CTL) recognize tumor antigen by MHC class I molecules. But most tumors are associated with a...
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Expression of Th1 and Th2 type cytokines responding to HBsAg and HBxAg in chronic hepatitis B patients

Lee M, Lee MA, Lee SK, Son M, Cho SW, Park S, Kim HI

The cytokine pattern on viral antigen recognition is believed to exert a profound influence on the resolution of viral infections and viral clearance. This study was initiated to investigate whether...
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Effect of polyadenylic.polyuridylic acid on cellular responses of peripheral blood mononuclear cells from patients with chronic active hepatitis B

Kim WH, Hahm KB, Park SJ, Kang JK, Park IS, Choi HJ, Shin JS, Youn JK

We have investigated in vitro proliferative responses of peripheral blood mononuclear cells and productions of interferon-gamma and soluble interleukin-2 receptors by these cells from 6 patients with chronic active hepatitis...
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Interleukin-1 beta, -6 and interferon-gamma productions in patients undergoing continuous ambulatory peritoneal dialysis

Choi KH, Lee IH, Shin SK, Noh HJ, Kang SW, Lee HY, Han DS

In order to investigate cytokine productions in patients undergoing continuous ambulatory peritoneal dialysis (CAPD), we studied the production of interleukin (IL)-1 beta, -6 and interferon (IFN)-gamma by cultured peripheral blood...
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Expression of NF-kappaB and Cytokines in Chronic Rejection of Transplanted Murine Heart

Lee JR, Seok CJ, Kim JS, Chang JM, Seo JW

The heart transplantation-associated accelerated graft arteriosclerosis (AGAS) is one of the major causes of cardiac allograft failure. We investigated the early time-course of expresssion patterns of cytokines, transcription factor, and...
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Activated natural killer cell-mediated immunity is required for the inhibition of tumor metastasis by dendritic cell vaccination

Kim A, Noh YW, Kim KD, Jang YS, Choe YK, Lim JS

  • KMID: 1123764
  • Exp Mol Med.
  • 2004 Oct;36(5):428-443.
Immunization with dendritic cells (DCs) pulsed with tumor antigen can activate tumor-specific cytotoxic T lymphocytes (CTL), which is responsible for tumor protection and regression. In this study, we examined whether...
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Murine Model of Buckwheat Allergy by Intragastric Sensitization with Fresh Buckwheat Flour Extract

Lee SY, Oh S, Lee K, Jang YJ, Sohn MH, Lee KE, Kim KE

Food allergies affect about 4% of the Korean population, and buckwheat allergy is one of the most severe food allergies in Korea. The purpose of the present study was to...
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Sequential analysis of cell differentials and IFN-gamma production of splenocytes from mice infected with Toxoplasma gondii

Lee YH, Shin DW, Kasper LH

To assess the relationship between the changes of cellular components and the production of Th1 cytokine in the immune tissue, inbred C57BL/6 mice were orally infected with 40 cysts of...
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Ovalbumin fused with diphtheria toxin protects mice from ovalbumin induced anaphylactic shock

Lee BK, Yoo YG, Lee WY, Hong CS, Park JK, Ro JY

For those with allergy, vaccination with a specific allergen has often been used as a major therapeutic measure. However, the universal application of this technique in clinics...
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