- The Effect of 17beta- Estradiol on the Messenser Ribonucleic Acid ( mRNA ) Expression of Insulin-like Growth Factor Binding Proteins in Normal Myometrium and Uterine Leiomyoma
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Kim SS, Kim JK, Lee JY
- KMID: 1855595
- Korean J Obstet Gynecol.
- 1998 Jan;41(1):17-27.
Uterine leiomyoma is the most common female reproductive tract tumor during reproductive years. Estrogen has been implicated the most important factor in leimyoma growth. Recently studies have also implicated insulin-like... -
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- The Effect of Sex Steroid Hormone on the Expression of Insulin-Like Growth Factor Binding Preteins mRNA in the Explant Cultured from Human Uterine Myoma and Adjacent Normal Myometrium
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Lee JY, Kim JK, Seo CS, Kim SH, Choi YM, Moon SY
- KMID: 1853224
- J Korean Soc Endocrinol.
- 1998 Mar;13(1):34-44.
BACKGROUND: Sex steroid hormones are believed to play an important role in the genesis and growth of uterine myoma. Several studies suggest a possible role of insulin-like growth factor(IGF) as... -
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- The Tumor Suppressor Function of PTEN/MMAC1 through the Regulation of IGFs and IGFBPs
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Yi HK, Hwang DJ, Kim SY, Lee DY, Hwang PH
- KMID: 1875814
- Korean J Pediatr.
- 2004 Aug;47(8):884-891.
PURPOSE: PTEN/MMAC1, a novel tumor suppressor gene, is mutated in a variety of advanced and metastatic cancers. It acts as a phosphatase, and thereby, regulates the PI-3 kinase/Akt pathway. In... -
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- Expression of Human Insulin-Like Growth Factor Binding Protein ( IGFBP )-4 , 5 , 6 mRNA and Immunohistochemical Localization of IGFBP-4 in Human Fallopian Tube
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Choi DS, Lee JY
- KMID: 2260965
- Korean J Obstet Gynecol.
- 1998 May;41(5):1369-1383.
The fallopian tube is a dynamic structure where the epithelium undergoes sex steroid hormone-dependent specific changes and in which gamete transport, maturation, fertilization, and early embryo development and transport occur.... -
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- Transcriptional activation of insulin-like growth factor binding protein 6 by 17beta-estradiol in SaOS-2 cells
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Zhao YY, Guo L, Zhao XJ, Liu H, Lei T, Ma DJ, Gao XY
- KMID: 1058022
- Exp Mol Med.
- 2009 Jul;41(7):478-486.
- doi: 10.3858/emm.2009.41.7.053
Osteoblasts can synthesize the insulin-like growth factors (IGFs) and the IGF-binding proteins (IGFBPs), which may either enhance or attenuate IGF-stimulated bone cell proliferation. Since estrogen induced osteoblastic differentiation and proliferation... -
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