- Insulin-like growth factor (IGF)-I and IGF binding proteins axis in diabetes mellitus
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Kim MS, Lee DY
- KMID: 2368988
- Ann Pediatr Endocrinol Metab.
- 2015 Jun;20(2):69-73.
- doi: 10.6065/apem.2015.20.2.69
Increasing evidence suggests an important role of the insulin-like growth factor (IGF)-IGF binding protein (IGFBP) axis in the maintenance of normal glucose and lipid metabolism. Significant changes occur in the... -
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- Serum Insulin-like Growth Factor-1(IGF-1) and Insulin-like Growth Factor Binding Proteins in Hyperthyroidism and Hypothyroidism
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Song HM, Park SS, Park TS, Baek HS, Lee DY
- KMID: 2461604
- J Korean Soc Endocrinol.
- 1996 Mar;11(1):52-60.
Backgrounds: Thyroid hormones play a fundamental role in the initiation and maintenance of somatic growth in mammalian species, and the insulin-like growth factors(IGFs) occupy a position of central importance in... -
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- The Effect of 17beta- Estradiol on the Messenser Ribonucleic Acid ( mRNA ) Expression of Insulin-like Growth Factor Binding Proteins in Normal Myometrium and Uterine Leiomyoma
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Kim SS, Kim JK, Lee JY
- KMID: 1855595
- Korean J Obstet Gynecol.
- 1998 Jan;41(1):17-27.
Uterine leiomyoma is the most common female reproductive tract tumor during reproductive years. Estrogen has been implicated the most important factor in leimyoma growth. Recently studies have also implicated insulin-like... -
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- Insulin-Like Growth Factor Binding Proteins Profiles in Sera of Patients with Uterine Myoma Before and After Hystrectomy
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Noh KR, Kim JK
- KMID: 2260954
- Korean J Obstet Gynecol.
- 1998 May;41(5):1273-1283.
It has been suggested that insulin-like growth factor (IGF) system plays an pivotal role in the growth of uterine myoma. Recent reports have shown that serum IGF-I levels are normal... -
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- Insulin-like growth factor-I and II and insulin-like growth factor binding protein-3 in amniotic fluid at second trimester: A correlation with birth weight
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Kim JY, Yang SH, Lee IS
- KMID: 2076221
- Korean J Obstet Gynecol.
- 2001 Apr;44(4):668-673.
OBJECTIVE: o determine the correlation between birth weight and the level of insulin-like growth factor(IGF)-I, -II and insulin-like growth factor binding protein(IGFBP)-3 in amniotic fluid at second trimester and to... -
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- Profiles of Insulin-like Growth Factor[IGF]s , their Binding Protein[IGFBP]s and IGFBP-3 Protease Activity in Peritoneal Fluid of Patients with Endometriosis
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Kim JK, Suh CS, Kim SH, Choi YM, Moon SY, Kang SB, Lee JY
- KMID: 2269603
- Korean J Obstet Gynecol.
- 1999 May;42(5):1011-1017.
OBJECTIVES: To test if IGF[insulin-like growth factor] components in peritoneal fluid[PF] of patients with endometriosis may be involved in the growth of ectopic endometrium. METHODS: In peritoneal fluid[PF] obtained from... -
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- Levels of Insulin - like Growth Factor 1 ( IGF - 1 ) , Insulin - like Growth Factor Binding Protein 3 ( IGFBP - 3 ) , Osteocalcin and Deoxypyridinoline biochemical markers in either surgical menopause or natural menopause women
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Chough SY, Kim SK, Lee JK
- KMID: 2261326
- Korean J Obstet Gynecol.
- 1999 Feb;42(2):382-387.
OBJECTIVE: The purpose of this study was to investigate possible menopause related changes in circulating insulin-like growth factor binding protein 3 (IGFBP-3) levels and their relationship with insulin-like growth factor... -
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- Serum Levels of Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3 in Children with Idiopathic Short Stature
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Bae WJ, Jung JM, Chung WY
- KMID: 1482014
- J Korean Soc Pediatr Endocrinol.
- 2008 Dec;13(2):143-149.
PURPOSE: The aim of present study was to compare the mean serum levels of Insulin-like growth factor-I (IGF-I) and Insulin-like growth factor binding protein-3 (IGFBP-3) according to the Korean standard... -
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- Influence of Activin and Follistatin on Expression of Insulin-like Growth Factor (IGF)-I, II, Insulin-like Growth Factor Binding Protein (IGFBP)-1, 2, and 3 mRNA in Cultured Mouse Granulosa Cells
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Chae HD, Hong SH, Cho YH, Oh YM, Lee BH, Kim SH, Kim CH, Kang BM
- KMID: 2076847
- Korean J Obstet Gynecol.
- 2003 Mar;46(3):592-599.
OBJECTIVE: To investigate the influence of activin and follistatin on the expression of IGF (insulin-like growth factor)-I, II, IGFBP (insulin-like growth factor binding protein)-1, 2, and 3 mRNA in cultured... -
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- The Effect of Sex Steroid Hormone on the Expression of Insulin-Like Growth Factor Binding Preteins mRNA in the Explant Cultured from Human Uterine Myoma and Adjacent Normal Myometrium
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Lee JY, Kim JK, Seo CS, Kim SH, Choi YM, Moon SY
- KMID: 1853224
- J Korean Soc Endocrinol.
- 1998 Mar;13(1):34-44.
BACKGROUND: Sex steroid hormones are believed to play an important role in the genesis and growth of uterine myoma. Several studies suggest a possible role of insulin-like growth factor(IGF) as... -
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- Clinical Manifestation and Elevated Serum Insulin-like Growth Factor-1 (IGF-1) Levels with Post-adolescent Acne
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Shin MK, Kim NI
- KMID: 2248293
- Korean J Dermatol.
- 2008 May;46(5):619-626.
BACKGROUND: Acne has been recognized as a common disorder amongst adolescents but recent studies have documented increased prevalence of post-adolescent acne. OBJECTIVE: The purpose of this study was to demonstrate insulin... -
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- The levels of insulin-like growth factor-binding proteins and their protease activity in serum and follicular fluid during the controlled ovarian hyperstimulation cycle
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Kim JG, Suh CS, Kim SH, Choi YM, Moon SY, Lee YH, Lee JY
- KMID: 2269998
- Korean J Obstet Gynecol.
- 2000 Mar;43(3):488-496.
OBJECTIVES: To evaluate changes in serum insulin-like growth factor binding protein(IGFBP)s profiles during the controlled hyperstimulation cycle and to compare IGFBPs profiles and their protease activity in follicular fluid(FF) from polycystic ovary... -
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- Evaluation of Serum Insulin-Like Growth Factor(IGF)-I, Insulin-Like Growth Factor Binding Protein(IGFBP)-2 and IGFBP-3 Levels in Healthy Korean Children
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Yang GH, Jung HL, Kim DS, Shim JW, Shim JY, Park MS
- KMID: 1979728
- Korean J Pediatr.
- 2005 Mar;48(3):298-305.
PURPOSE: We performed this study to evaluate the mean serum levels of insulin-like growth factor (IGF)-I, insulin-like growth factor binding protein(IGFBP)-2 and IGFBP-3 in healthy Korean children according to age... -
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- Insulin-Like Growth Factors and Their Bindign Proteins in Uterine Leiomyoma Pretreated with Gonadtropin Releasing Hormone Agonist
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Kim KC, Kim JG, Lee JY
- KMID: 1999282
- J Korean Soc Endocrinol.
- 1997 Sep;12(3):364-375.
BACKGROUND: Uterine leiomyoma is the most common pelvic tumor, occurring in 20-25% of women in reproductive age. Gonadotropin releasing hormone agonist (GnRHa) has been reognized as a temporary medical management... -
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- The Expression of Insulin-like Growth Factor (IGF), IGF- Binding Protein (IGFBP) and the Role of IGFBP-3 in the Korean Gastric Cancer Cell Lines
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Lee DY, Yi HK, Yang DH, Hwang PH
- KMID: 2174986
- J Korean Cancer Assoc.
- 2001 Apr;33(2):121-129.
PURPOSE: Insulin-like growth factor (IGF)-I and II are potent mitogens, postulated to exert autocrine and paracrine effects on growth regulation in human gastric cancer. In this study, we evaluated the... -
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- The Effects of a Gonadotropin Releasing Hormone agonist on Insulin-like Growth Factor Binding Proteins(IGFBPs) Production in Explant Cultures of Human Uterine Myoma and Normal Myometrium
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Kim JG, Suh CS, Kim SH, Choi YM, Moon SY, Lee JY
- KMID: 2260784
- Korean J Obstet Gynecol.
- 1997 Apr;40(4):758-766.
Gonadotropin releasing hormone agonist(GnRHa) has been used as a temporaruy medical management for uterine myoma. Insulin-like growth factors(IGFs) has been supposed to play an etiological role in myoma growth and... -
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- Growth Status and Levels of Growth Factors in Children with Insulin-dependent Diabetes Mellitus
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Chung SC, Kim DH
- KMID: 2335360
- J Korean Pediatr Soc.
- 1998 Aug;41(8):1102-1110.
PURPOSE: It is well known that the linear growth velocity in children with insulin-dependent diabetes mellitus (type 1 DM) is closely related to metabolic control and onset age of the... -
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- Insulin-like Growth Factor(IGF)-I and IGF-Binding Protein-3 in Relation to Hemoglobin Concentration in Healthy Infants
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Kang YK, Lee DY
- KMID: 2335499
- J Korean Pediatr Soc.
- 2000 Jul;43(7):967-973.
PURPOSE: Insulin-like growth factor(IGF-I) and IGF binding protein(IGFBP)-3 is thought to play an important role in fetal erythropoiesis. The objective of this study was to establish a relation between IGF-I, free IGF-I,... -
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- The Tumor Suppressor Function of PTEN/MMAC1 through the Regulation of IGFs and IGFBPs
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Yi HK, Hwang DJ, Kim SY, Lee DY, Hwang PH
- KMID: 1875814
- Korean J Pediatr.
- 2004 Aug;47(8):884-891.
PURPOSE: PTEN/MMAC1, a novel tumor suppressor gene, is mutated in a variety of advanced and metastatic cancers. It acts as a phosphatase, and thereby, regulates the PI-3 kinase/Akt pathway. In... -
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- Serum levels of free insulin-like growth factor-I and clinical value in healthy children
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Chung YH, Chung WY
- KMID: 1487158
- Korean J Pediatr.
- 2008 Jan;51(1):47-53.
- doi: 10.3345/kjp.2008.51.1.47
Background: The serum levels of total insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3 reflect endogenous growth hormone (GH) secretion in healthy children. Free form of IGF-I which is... -
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