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Towards developing a diagnostic regimen for the treatment follow-up of Trypanosoma brucei gambiense

Mbati PA, Hirumi K, Inoue N, Situakibanza NH, Hirumi H

BALB/c mice infected with a high virulent strain of Trypanosoma brucei gambiense IL3707 were treated intraperitoneally (ip) with either Melarsoprol (Mel-B) or PSG(+) buffer as controls. The mice were subsequently...
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Clinical evaluation of pediatric anaphylaxis and the necessity for multiple doses of epinephrine

Inoue N, Yamamoto A

BACKGROUND: Epinephrine administered intramuscularly is the treatment of choice for anaphylaxis, and more than 1 dose is occasionally required. OBJECTIVE: To determine clinical background of anaphylaxis for improving the treatment, management,...
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Biomechanical and Anatomical Validity of the Short Posterior Arch Screw

Mizutani J, Inoue N, Otsuka Y, Furuya A, Espinoza Orias AA, Otsuka T

OBJECTIVE: This study was conducted to clarify the validity of the short posterior arch screw (S-PAS). The S-PAS is inserted only in the pedicle-analogue portion of the posterior arch. The...
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Image-Based Markers Predict Dynamic Instability in Lumbar Degenerative Spondylolisthesis

III WS, Orías AAE, Shifflett , Lee JY, Siemionow , Gandhi S, Fogg L, Samartzis , Inoue N, An HS

Objective: To identify possible radiographic predictors markers of dynamic instability including disc height (DH), disc degeneration, and spondylosis in the setting of degenerative spondylolisthesis (DS). Methods: A retrospective review with prospectively...
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5-Aminosalicylic acid aggravates colitis mimicking exacerbation of ulcerative colitis

Miyoshi J, Matsuoka K, Yoshida A, Naganuma M, Hisamatsu , Yajima T, Inoue N, Okamoto S, Iwao Y, Ogata H, Ueno F, Hibi T, Kanai T

Ulcerative colitis (UC) is one of the major clinical phenotypes of inflammatory bowel diseases. Although 5-aminosalicylic acid (5-ASA) is widely used for UC and its efficacy and safety have been...
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Pathophysiology of Diabetic Retinopathy: The Old and the New

Kusuhara S, Fukushima , Ogura S, Inoue N, Uemura A

Vision loss in diabetic retinopathy (DR) is ascribed primarily to retinal vascular abnormalities—including hyperpermeability, hypoperfusion, and neoangiogenesis—that eventually lead to anatomical and functional alterations in retinal neurons and glial cells....
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Long-term safety and efficacy of adalimumab for intestinal Behçet's disease in the open label study following a phase 3 clinical trial

Inoue N, Kobayashi , Naganuma M, Hirai F, Ozawa M, Arikan D, Huang B, Robinson A, Thakkar RB, Hibi T

BACKGROUND/AIMS: Intestinal Behçet's disease (BD) is an immune-mediated inflammatory disorder. We followed up the patients and evaluated safety profile and effectiveness of adalimumab for the treatment of intestinal BD through...
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Loop-Mediated Isothermal Amplification Targeting 18S Ribosomal DNA for Rapid Detection of Acanthamoeba

Yang HW, Lee YR, Inoue N, Jha BK, Danne DB, Kim HK, Lee J, Goo YK, Kong HH, Chung DI, Hong Y

Amoebic keratitis (AK) caused by Acanthamoeba is one of the most serious corneal infections. AK is frequently misdiagnosed initially as viral, bacterial, or fungal keratitis, thus ensuring treatment delays. Accordingly,...
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Development of Loop-Mediated Isothermal Amplification Targeting 18S Ribosomal DNA for Rapid Detection of Azumiobodo hoyamushi (Kinetoplastea)

Song SM, Sylvatrie-Danne DB, Joo SY, Shin YK, Yu HS, Lee YS, Jung JE, Inoue N, Lee WK, Goo YK, Chung DI, Hong Y

  • KMID: 1792187
  • Korean J Parasitol.
  • 2014 Jun;52(3):305-310.
Ascidian soft tunic syndrome (AsSTS) caused by Azumiobodo hoyamushi (A. hoyamushi) is a serious aquaculture problem that results in mass mortality of ascidians. Accordingly, the early and accurate detection of...
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