- The Frequency and the Course of the Adverse Effects of Azathioprine/6-Mercaptopurine Treatment in Patients with Inflammatory Bowel Disease
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Cha JM, Kim HJ
- KMID: 1767534
- Korean J Gastroenterol.
- 2008 May;51(5):319-322.
No abstract available. -
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- Inflammatory Bowel Disease: Updates on Molecular Targets for Biologics
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Katsanos K, Papadakis
- KMID: 2412224
- Gut Liver.
- 2017 Jul;11(4):455-463.
- doi: 10.5009/gnl16308
Therapy for inflammatory bowel disease (IBD) has changed, with several new agents being evaluated. The era of anti-tumor necrosis factor (anti-TNF) antibody therapy saw remarkable progress in IBD therapy. Some... -
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- Differences in the Adverse Effects of Azathioprine between Inflammatory Bowel Disease and Autoimmune Hepatitis in Korean Patients
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Lee YJ, Choi WY, Park KS, Kim YJ, Cho KB, Kim ES, Jang BK, Chung WJ, Hwang JS
- KMID: 2160667
- Korean J Gastroenterol.
- 2014 Dec;64(6):348-355.
- doi: 10.4166/kjg.2014.64.6.348
BACKGROUND/AIMS: Azathioprine (AZA) has been widely used in the therapy of inflammatory bowel disease (IBD) and autoimmune hepatitis (AIH). However, studies evaluating the adverse effects of AZA in these two... -
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- The Frequency and the Course of the Adverse Effects of Azathioprine/6-Mercaptopurine Treatment in Patients with Inflammatory Bowel Disease
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Kim JH, Cheon JH, Kim WH
- KMID: 1767529
- Korean J Gastroenterol.
- 2008 May;51(5):291-297.
BACKGROUND/AIMS: This study was to evaluate the frequency and the course of the adverse effects of AZA/6-MP in Korean patients with inflammatory bowel disease (IBD). METHODS: Medical records of the... -
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- Successful Azathioprine Treatment with Metabolite Monitoring in a Pediatric Inflammatory Bowel Disease Patient Homozygous for TPMT*3C
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Lee MN, Woo HI, Lee YM, Kang B, Kim JW, Choe YH, Lee SY
- KMID: 1798157
- Yonsei Med J.
- 2013 Nov;54(6):1545-1549.
- doi: 10.3349/ymj.2013.54.6.1545
Thiopurine S-methyltransferase (TPMT) methylates purine analogues, showing TPMT activity in inverse relation to concentrations of active metabolites such as 6-thioguanine nucleotide (6-TGN). With conventional dosing of thiopurines, patients with homozygous... -
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- The Association between the Therapeutic Agent and the Compliance of the Patients with Inflammatory Bowel Diseases
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Kang YS, Kim SY, Jo MH, Kang HW, Lee JK, Lim YJ, Koh MS, Lee JH, Yang CH, Kim JH
- KMID: 1718062
- Korean J Gastroenterol.
- 2013 Jun;61(6):313-318.
- doi: 10.4166/kjg.2013.61.6.313
BACKGROUND/AIMS: Adherence of the patients with inflammatory bowel diseases is important to maintain the remission. However, the patients do not always keep their appointments for treatment. The aim of this... -
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- Effects of Probiotics on Gut Microbiota in Patients with Inflammatory Bowel Disease: A Double-blind, Placebo-controlled Clinical Trial
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Shadnoush , Hosseini R, Khalilnezhad A, Navai L, Goudarzi H, Vaezjalali M
- KMID: 2373212
- Korean J Gastroenterol.
- 2015 Apr;65(4):215-221.
- doi: 10.4166/kjg.2015.65.4.215
BACKGROUND/AIMS: Several clinical trials have revealed various advantages for probiotics in inflammatory bowel disease (IBD). The aim of this study was to further investigate the effects of probiotic yogurt consumption... -
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- Monitoring Thiopurine Metabolites in Korean Pediatric Patients with Inflammatory Bowel Disease
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Kim MJ, Lee SY, Choe YH
- KMID: 1799493
- Yonsei Med J.
- 2014 Sep;55(5):1289-1296.
- doi: 10.3349/ymj.2014.55.5.1289
PURPOSE: This study aimed to assess the role of thiopurine S-methyltransferase (TPMT) and 6-thioguanine nucleotide (6-TGN) as predictors of clinical response and side effects to azathioprine (AZA), and estimate the... -
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