- Growth Factor Receptor Expression on Brain Tumor Cell Lines : Preliminary Study for in vitro and in vivo Experiments of Immunotoxin Therapy
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Kim KU, Ni HT, Low WC, Hall WA
- KMID: 1547607
- J Korean Neurosurg Soc.
- 2000 Jun;29(6):731-739.
No abstract available. -
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- The Basic Studies on the Application of Galectin - 3 as a Target Protein for Delivering Anticancer Agents
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Woo HJ, Joo HG
- KMID: 1547844
- Korean J Immunol.
- 1997 Mar;19(1):83-90.
Gastric cancer cells express large amounts of galectin-3 on the cell surface. This fact may provide the possibility to use galectin-3 protein as a surface target for delivering cytotoxic anticancer... -
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- Human Immunodeficiency Virus-Infected T Cells Are Selectively Killed by Monoclonal Anti-gp120 Antibody Coupled to Pokeweed Antiviral Protein
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Kang MR, Kim SY, Kim YK, Hong HJ, Cho MH, Shin HS
- KMID: 2096722
- J Korean Soc Virol.
- 1998 Dec;28(4):383-391.
A murime monoclonal antibody (mAb) specific for the envelope glycoprotein gp120 of human immunodeficiency virus type-I (HIV-1) was chemically coupled to pokeweed antiviral protein (PAP) from Phytolacca americana. The immunotoxin... -
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- Nucleic Acid Aptamers: New Methods for Selection, Stabilization, and Application in Biomedical Science
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Kong HY, Byun J
- KMID: 2170659
- Biomol Ther.
- 2013 Nov;21(6):423-434.
The adoption of oligonucleotide aptamer is well on the rise, serving an ever increasing demand for versatility in biomedical field. Through the SELEX (Systematic Evolution of Ligands by EXponential enrichment),... -
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- Continuous Intratumoral Delivery of Chemotherapeutic Agent by Convection-enhanced Technique: Preliminary Clinical Study
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Song YJ, Kim KU, Jung DG, Choi SS, Huh GY, Seo SY
- KMID: 2339788
- J Korean Neurosurg Soc.
- 2004 Mar;35(3):240-245.
OBJECTIVE: Because of the limited penetration into the central nervous system after systemic administration of numerous therapeutic compounds, intratumoral chemotherapy for brain tumors has also been used. However, the efficacy... -
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- Expression of Cell Surface Receptors on Human Glioblastoma Xenograft Model in NOD/SCID Mouse
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Oh KS, Kim KU, Park NH, Seo SY, Choi SS, Huh GY
- KMID: 1972969
- Cancer Res Treat.
- 2002 Feb;34(1):52-57.
PURPOSE: To obtain basic data for development of a glioblastoma-specific immunotoxin, the expression of variable cell surface receptors on a human glioblastoma xenograft model was evaluated, using NOD/SCID mice. MATERIALS AND... -
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- Cytotoxicity of OKT9 ScFv-Diphtheria Toxin Fusion Immunotoxin on Human Brain Tumor Cell Lines
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Back OK, Song YJ, Lee HW, Park NH, Kim YC, Seo SY, Kim KU
- KMID: 1905019
- J Korean Neurosurg Soc.
- 2004 Jul;36(1):59-65.
OBJECTIVE: Immunotoxin therapy is a novel approach for the treatment of tumor, and it has been successfully used in the central nervous system. The purpose of this study is to... -
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- Antiproliferative effect of basic fibroblast growth factor-saporin mitotoxin on keratocytes in culture
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Wee WR, Parandoosh Z, Sakamoto T, Caton M, Nova M, McDonnell
- KMID: 1735150
- Korean J Ophthalmol.
- 1996 Jun;10(1):1-7.
- doi: 10.3341/kjo.1996.10.1.1
We evaluated the effect of the conjugate of basic fibroblast growth factor (FGF2) and saporin (FGF2-SAP) on proliferation of cultured keratocytes. Cultured rabbit and human keratocytes were incubated in medium... -
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- Thermo-stability and antitumor activity on colon cancer cell lines of monoclonal anti-CEA antibody-saporin immunotoxin
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Manosroi J, Kleist SV, Manosroi A, Grunert F
- KMID: 1421902
- J Korean Med Sci.
- 1992 Jun;7(2):128-135.
- doi: 10.3346/jkms.1992.7.2.128
Eight saporin peaks were obtained from the purification of seed extracts of Saponaria officinalis L. Saporin peak No. 6 (SAP-6) showed the highest activity in the inhibition of protein... -
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- Novel Vaccine Development against Escherichia coli O157: Immunologic Properties of O-Specific Polysaccharide-Shiga-like Toxin Conjugate Vaccines
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Kim GY, Choi SK, An WG, Oh YH, Park YM
- KMID: 1615422
- J Bacteriol Virol.
- 2003 Mar;33(1):27-38.
Escherichia coli (E. coli) O157:H7 is an important cause of hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). LPS-based vaccines need improvement since the anti-LPS antibodies raised by the vaccines... -
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