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TGF-beta-treated antigen presenting cells suppress collagen-induced arthritis through the promotion of Th2 responses

Jung S, Park YK, Lee H, Shin JH, Lee GR, Park SH

Collagen-induced arthritis (CIA) is mediated by self-reactive CD4+ T cells that produce inflammatory cytokines. TGF-beta2-treated tolerogenic antigen-presenting cells (Tol-APCs) are known to induce tolerance in various autoimmune diseases. In this...
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Immune Tolerance of Human Dental Pulp-Derived Mesenchymal Stem Cells Mediated by CD4⁺CD25⁺FoxP3⁺ Regulatory T-Cells and Induced by TGF-β1 and IL-10

Hong JW, Lim JH, Chung CJ, Kang TJ, Kim TY, Kim YS, Roh TS, Lew DH

PURPOSE: Most studies on immune tolerance of mesenchymal stem cells (MSCs) have been performed using MSCs derived from bone marrow, cord blood, or adipose tissue. MSCs also exist in the...
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In vitro effects of meloxicam on the number, Foxp3 expression, production of selected cytokines, and apoptosis of bovine CD25+CD4+ and CD25-CD4+ cells

Maslanka T, Jaroszewski JJ

The purpose of this study was to evaluate the effect of meloxicam (MEL) on selected immune parameters of bovine CD25highCD4+, CD25lowCD4+, and CD25-CD4+ cells. Peripheral blood mononuclear cells (PBMCs) collected...
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Effects of Antipsychotic Drugs on Cellular lmmunity in Mice

Kim KH

The effects of the two antipsychotic drugs, chlorpromazine and haloperidol, the focus of this study, on cell-mediated immunity in male ICR mice. The peripheral blood WBC count decreased significantly in...
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