- Potential Roles of Innate Immune Chemokine and Cytokine Network on Lipopolysaccharide-Based Therapeutic Approach in Ovarian Cancer
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Ignacio RM, Lee ES, Son DS
- KMID: 2450207
- Immune Netw.
- 2019 Jun;19(3):e22.
- doi: 10.4110/in.2019.19.e22
Ovarian cancer (OC), the deadliest gynecological cancer, results in poor overall survival, urgently requiring a novel therapeutic approach. As cumulative exposures to endotoxins decreased OC risk epidemiologically, we evaluated if... -
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- Polymeric Nanoparticles Containing Both Antigen and Vitamin D₃ Induce Antigen-Specific Immune Suppression
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Jung HH, Kim SH, Moon JH, Jeong SU, Jang S, Park CS, Lee CK
- KMID: 2450204
- Immune Netw.
- 2019 Jun;19(3):e19.
- doi: 10.4110/in.2019.19.e19
The active form of vitamin D3, 1,25-dihydroxyvitamin D₃ (aVD₃), is known to exert beneficial effects in the treatment of autoimmune diseases because of its immunosuppressive effects. However, clinical application of... -
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- Galectin-4 Interaction with CD14 Triggers the Differentiation of Monocytes into Macrophage-like Cells via the MAPK Signaling Pathway
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Hong SH, Shin JS, Chung H, Park CG
- KMID: 2450202
- Immune Netw.
- 2019 Jun;19(3):e17.
- doi: 10.4110/in.2019.19.e17
Galectin-4 (Gal-4) is a β-galactoside-binding protein mostly expressed in the gastrointestinal tract of animals. Although intensive functional studies have been done for other galectin isoforms, the immunoregulatory function of Gal-4... -
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- Respiratory Syncytial Virus Fusion Protein-encoding DNA Vaccine Is Less Effective in Conferring Protection against Inflammatory Disease than a Virus-like Particle Platform
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Kwon YM, Hwang HS, Lee YT, Kim KH, Lee Y, Kim MC, Lee YN, Quan FS, Moore ML, Kang SM
- KMID: 2450203
- Immune Netw.
- 2019 Jun;19(3):e18.
- doi: 10.4110/in.2019.19.e18
Formalin-inactivated respiratory syncytial virus (RSV) vaccination causes vaccine-enhanced disease (VED) after RSV infection. It is considered that vaccine platforms enabling endogenous synthesis of RSV immunogens would induce favorable immune responses... -
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- Prominent Inflammatory Features of Monocytes/Macrophages in Acute Calcium Pyrophosphate Crystal Arthritis: a Comparison with Acute Gouty Arthritis
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Jeong JH, Jung JH, Lee JS, Oh JS, Kim YG, Lee CK, Yoo B, Hong S
- KMID: 2450206
- Immune Netw.
- 2019 Jun;19(3):e21.
- doi: 10.4110/in.2019.19.e21
Calcium pyrophosphate (CPP) crystals can present as acute inflammatory arthritis which is known as an acute CPP crystal arthritis. Although monocytes/macrophages have been shown to play a role in the... -
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- Dimerized, Not Monomeric, Translationally Controlled Tumor Protein Induces Basophil Activation and Mast Cell Degranulation in Chronic Urticaria
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Ulambayar , Lee H, Yang EM, Park HS, Lee K, Ye YM
- KMID: 2450205
- Immune Netw.
- 2019 Jun;19(3):e20.
- doi: 10.4110/in.2019.19.e20
Translationally controlled tumor protein (TCTP) is also known as histamine releasing factor as it has the ability to activate mast cells. To investigate the role of TCTP in the pathogenesis... -
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- p62 Negatively Regulates TLR4 Signaling via Functional Regulation of the TRAF6-ECSIT Complex
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Kim MJ, Min Y, Kwon J, Son J, Im JS, Shin J, Lee KY
- KMID: 2450201
- Immune Netw.
- 2019 Jun;19(3):e16.
- doi: 10.4110/in.2019.19.e16
Sequestosome 1 (SQSTM1, p62), a ubiquitin binding protein, plays a role in cell signaling, oxidative stress, and autophagy. However, its functional role in inflammatory signaling is controversial. Recent studies have... -
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- Two Distinct Subsets Are Identified from the Peritoneal Myeloid Mononuclear Cells Expressing both CD11c and CD115
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Sohn M, Na HY, Ryu SH, Choi W, In H, Shin HS, Park JS, Shim D, Shin SJ, Park CG
- KMID: 2450200
- Immune Netw.
- 2019 Jun;19(3):e15.
- doi: 10.4110/in.2019.19.e15
To this date, the criteria to distinguish peritoneal macrophages and dendritic cells (DCs) are not clear. Here we delineate the subsets of myeloid mononuclear cells in the mouse peritoneal cavity.... -
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