- Aging and the Immune System: the Impact of Immunosenescence on Viral Infection, Immunity and Vaccine Immunogenicity
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Oh SJ, Lee JK, Shin OS
- KMID: 2466607
- Immune Netw.
- 2019 Dec;19(6):e37.
- doi: 10.4110/in.2019.19.e37
Immunosenescence is characterized by a progressive deterioration of the immune system associated with aging. Multiple components of both innate and adaptive immune systems experience aging-related changes, such as alterations in... -
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- Human Immunity Against Campylobacter Infection
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Hameed A
- KMID: 2466608
- Immune Netw.
- 2019 Dec;19(6):e38.
- doi: 10.4110/in.2019.19.e38
Campylobacter is a worldwide foodborne pathogen, associated with human gastroenteritis. The efficient translocation of Campylobacter and its ability to secrete toxins into host cells are the 2 key features of... -
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- Evaluating Antitumor Activity of Kiatomab by Targeting Cancer Stem Cell-Specific KIAA1114 Antigen in Mice
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Kim SW, Park HW, Kim H, Lee S, Choi SY, Park Y, Lee SW
- KMID: 2466613
- Immune Netw.
- 2019 Dec;19(6):e43.
- doi: 10.4110/in.2019.19.e43
A full-length translational product of the trophinin gene, KIAA1114, is a distinctive marker of cancer stem cells in human hepatocellular carcinoma, and a mAb, Kiatomab, is specific to KIAA1114 antigen.... -
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- Lactobacillus pentosus Modulates Immune Response by Inducing IL-10 Producing Tr1 Cells
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Kim JE, Sharma A, Sharma G, Lee SY, Shin HS, Rudra D, Im SH
- KMID: 2466609
- Immune Netw.
- 2019 Dec;19(6):e39.
- doi: 10.4110/in.2019.19.e39
Several gut commensals have been shown to modulate host immune response. Recently, many food derived microbes have also been reported to affect the immune system. However, a mechanism to identify... -
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- Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner
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Gim E, Shim DW, Hwang I, Shin OS, Yu JW
- KMID: 2466610
- Immune Netw.
- 2019 Dec;19(6):e40.
- doi: 10.4110/in.2019.19.e40
Zika virus (ZIKV) is a mosquito-borne flavivirus associated with severe neurological disorders including Guillain-Barré syndrome and microcephaly. The host innate immune responses against ZIKV infection are essential for protection; however,... -
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- Autoantibody-Mediated Dysfunction of Salivary Glands Leads to Xerostomia in SKG Mice
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Choi SS, Jang E, Jang K, Jung SJ, Hwang KG, Youn J
- KMID: 2466614
- Immune Netw.
- 2019 Dec;19(6):e44.
- doi: 10.4110/in.2019.19.e44
Sjögren's syndrome (SS) is a chronic heterogeneous disease that mainly affects exocrine glands, leading to sicca syndromes such as xerostomia. Despite the second highest prevalence rate among systemic autoimmune diseases,... -
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- Prenatal Exposure to Lead and Chromium is Associated with IL-13 Levels in Umbilical Cord Blood and Severity of Atopic Dermatitis: COCOA Study
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Kim J, Kim S, Woo SY, Chung JY, Hong YS, Oh SY, Choi SJ, Oh SY, Kim KW, Shin YH, Won HS, Lee KJ, Kim SH, Kwon JY, Lee SH, Hong SJ, Ahn K
- KMID: 2466612
- Immune Netw.
- 2019 Dec;19(6):e42.
- doi: 10.4110/in.2019.19.e42
There have been few studies investigating the association between atopic dermatitis (AD) and prenatal exposure to heavy metals. We aimed to evaluate whether prenatal exposure to heavy metals is associated... -
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- A Critical Role of PCSK9 in Mediating IL-17-Producing T Cell Responses in Hyperlipidemia
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Kim YU, Kee P, Danila D, Teng BB
- KMID: 2466611
- Immune Netw.
- 2019 Dec;19(6):e41.
- doi: 10.4110/in.2019.19.e41
We previously demonstrated that atherogenic Ldlr(−/−)Apobec1(−/−) (LDb) double knockout mice lacking both low-density lipoprotein receptor (LDLR) and apolipoprotein B mRNA-editing catalytic polypeptide-1 (Apobec1) had increased serum IL-17 levels, with T... -
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