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Effect of Lipofectin on Antigen-presenting Function and Anti-tumor Activity of Dendritic Cells

Noh YW, Lim JS

BACKGROUND: Dendritic cells (DC) are professional antigen-presenting cells in the immune system and can induce T cell response against virus infections, microbial pathogens, and tumors. Therefore, immunization using DC loaded...
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The Kinetics of Secondary Response of Antigen-Specific CD4+ T Cells Primed in vitro with Antigen

Park SO, Han YW, Aleyas AG, George JA, Yoon HA, Eo SK

BACKGROUND: Memory T lymphocytes of the immune system provide long-term protection in response to bacterial or viral infections/immunization. Ag concentration has also been postulated to be important in determining whether...
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Effect of Geranti Bio-Ge Yeast, a Dried Yeast Containing Biogermanium, on the Production of Antibodies by B Cells

Joo SS, Won TJ, Lee YJ, Kim MJ, Park SY, Lee SH, Hwang KW, Lee DI

BACKGROUND: Germanium compounds are increased to use in nutrient foods and medicines in terms of antibiotics to microbes, anticancer, modulation of immune system and neutralizing heavy metal toxins. Geranti Bio-Ge...
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Investigation of Chemotactic Activities in Differentiated HL-60 Cells by a Time-lapse Videomicroscopic Assay

Jung YJ, Woo SY, Ryu KH, Jang MH, Miyasaka M, Seoh JY

BACKGROUND: Chemotaxis is one of the cardinal functions of leukocytes, which enables them to be recruited efficiently to the right place at the right time. Analyzing chemotactic activities is important...
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Association of Killer Cell Ig-like Receptor (KIR) with an Adaptor Protein Shc

Cho HI, Chwae YJ, Park SM, Kim J

BACKGROUND: Cytotoxic function of killer cells is inhibited by specific recognition of class I MHC molecules on target cells by inhibitory killer Ig-like receptors (KIR) expressed on NK cells and...
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CM1 Ligation Induces Apoptosis via Fas-FasL Interaction in Ramos Cells, but via Down-regulation of Bcl-2 and Subsequent Decrease of Mitochondrial Membrane Potential in Raji Cells

Lee YS, Kim YS, Kim D, Hur DY, Kang JS, Kim YI, Hahm E, Cho D, Hwang YI, Lee WJ

BACKGROUND: CM1 (Centrocyte/-blast Marker I) defined by a mAb developed against concanavalin-A activated PBMC, is expressed specifically on a subpopulation of centroblasts and centrocytes of human germinal center (GC) B...
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