- CTLA-4-Tg/CD-28-KO Mice Exhibit Reduced T Cell Proliferation in vivo Compared to CD-28-KO Mice in a Graft-versus-host Disease Model
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Yoo JS, Lee YJ, Yoon JW, Hyung KE, Hwang KW
- KMID: 1493969
- Korean J Physiol Pharmacol.
- 2012 Oct;16(5):349-353.
- doi: 10.4196/kjpp.2012.16.5.349
Activated T cells express inhibitory receptors such as CTLA-4 that can downregulate immune responses. Blockade of or genetic deficiency in CTLA-4 can result in autoimmunity. Therefore, strategies to increase the... -
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- Bcl-2 Knockdown Accelerates T Cell Receptor-Triggered Activation-Induced Cell Death in Jurkat T Cells
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Lee YJ, Won TJ, Hyung KE, Lee MJ, Moon YH, Lee IH, Go BS, Hwang KW
- KMID: 2285494
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):73-78.
- doi: 10.4196/kjpp.2014.18.1.73
Cell death and survival are tightly controlled through the highly coordinated activation/inhibition of diverse signal transduction pathways to insure normal development and physiology. Imbalance between cell death and survival often... -
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- Effect of PRX-1 Downregulation in the Type 1 Diabetes Microenvironment
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Yoo JS, Lee YJ, Hyung KE, Yoon JW, Lee IH, Park SY, Hwang KW
- KMID: 2285456
- Korean J Physiol Pharmacol.
- 2012 Dec;16(6):463-468.
- doi: 10.4196/kjpp.2012.16.6.463
Type 1 diabetes (T1D) is caused by dysregulation of the immune system in the pancreatic islets, which eventually leads to insulin-producing pancreatic beta-cell death and destabilization of glucose homeostasis. One... -
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- Therapeutic effects of orally administered CJLP55 for atopic dermatitis via the regulation of immune response
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Hyung KE, Kim SJ, Jang YW, Lee DK, Hyun KH, Moon BS, Kim B, Ahn H, Park SY, Sohn UD, Park ES, Hwang KW
- KMID: 2376962
- Korean J Physiol Pharmacol.
- 2017 May;21(3):335-343.
- doi: 10.4196/kjpp.2017.21.3.335
Atopic dermatitis (AD) is an inflammatory skin condition accompanied by symptoms such as edema and hemorrhage. Kimchi is a traditional fermented Korean dish consisting of various probiotics. In this study,... -
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