- The pleckstrin homology domain of phospholipase D1 accelerates EGFR endocytosis by increasing the expression of the Rab5 effector, rabaptin-5
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Park MH, Choi KY, Min DS
- KMID: 2359887
- Exp Mol Med.
- 2015 Dec;47(12):e200.
- doi: 10.1038/emm.2015.101
Endocytosis is differentially regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) and phospholipase D (PLD). However, the relationship between HIF-1alpha and PLD in endocytosis is unknown. HIF-1alpha is degraded through the prolyl hydroxylase... -
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- Effects of Omega-3 Fatty Acids on Erectile Dysfunction in a Rat Model of Atherosclerosis-induced Chronic Pelvic Ischemia
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Shim JS, Kim DH, Bae JH, Moon DG
- KMID: 2363698
- J Korean Med Sci.
- 2016 Apr;31(4):585-589.
- doi: 10.3346/jkms.2016.31.4.585
The aim of this study was to investigate whether the omega-3 fatty acids help to improve erectile function in an atherosclerosis-induced erectile dysfunction rat model. A total of 20 male... -
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- Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells
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Hwang JE, Lee JH, Park MR, Kim DE, Bae WK, Shim HJ, Cho SH, Chung IJ
- KMID: 1503899
- Yonsei Med J.
- 2013 Mar;54(2):374-380.
- doi: 10.3349/ymj.2013.54.2.374
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1alpha. Recent reports suggested that HIF-1alpha also mediated... -
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- Effect of Endogenous Bone Marrow Derived Stem Cells Induced by AMD-3100 on Expanded Ischemic Flap
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Jeong HS, Lee HK, Tark KC, Lew DH, Koh YW, Kim CH, Seo IS
- KMID: 2151419
- J Korean Med Sci.
- 2014 Nov;29(Suppl 3):S237-S248.
- doi: 10.3346/jkms.2014.29.S3.S237
The purpose of this study was to devise an expanded ischemic flap model and to investigate the role of AMD-3100 (Plerixafor, chemokine receptor 4 inhibitor) in this model by confirming... -
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