- Urinary Hypoxia-Inducible Factor-1alpha Levels Are Associated with Histologic Chronicity Changes and Renal Function in Patients with Lupus Nephritis
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Ma C, Wei J, Zhan F, Wang R, Fu K, Wan X, Li Z
- KMID: 1776995
- Yonsei Med J.
- 2012 May;53(3):587-592.
- doi: 10.3349/ymj.2012.53.3.587
PURPOSE: Tubulointerstitial hypoxia in the kidney is considered a hallmark of injury and a mediator of the progression of tubulointerstitial fibrosis. Hypoxia-inducible factor-1alpha (HIF-1alpha), a master transcription factor in cellular... -
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