- Hypoxia-inducible factor 1, hepatocellular carcinoma and angiogenesis
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Kim JW
- KMID: 1717321
- Korean J Hepatol.
- 2010 Sep;16(3):278-279.
- doi: 10.3350/kjhep.2010.16.3.278
No abstract available. -
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- Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy
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Yu T, Tang B, Sun X
- KMID: 2419104
- Yonsei Med J.
- 2017 May;58(3):489-496.
- doi: 10.3349/ymj.2017.58.3.489
Hypoxia is frequently observed in solid tumors and also one of the major obstacles for effective cancer therapies. Cancer cells take advantage of their ability to adapt hypoxia to initiate... -
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- Effects of echinomycin on endothelin-2 expression and ovulation in immature rats primed with gonadotropins
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Wang Z, Zhang Z, Wu Y, Chen L, Luo Q, Zhang J, Chen J, Luo Z, Huang X, Cheng Y
- KMID: 1506225
- Exp Mol Med.
- 2012 Oct;44(10):615-621.
Echinomycin is a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity, which plays a crucial role in ovarian ovulation in mammalians. The present study was designed to test the hypothesis that... -
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- Effects of the knockdown of hypoxia inducible factor-1alpha expression by adenovirus-mediated shRNA on angiogenesis and tumor growth in hepatocellular carcinoma cell lines
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Choi SH, Shin HW, Park JY, Yoo JY, Kim DY, Ro WS, Yun CO, Han KH
- KMID: 1717322
- Korean J Hepatol.
- 2010 Sep;16(3):280-287.
- doi: 10.3350/kjhep.2010.16.3.280
BACKGROUND/AIMS: Hypoxia-inducible factor-1alpha (HIF-1alpha) is a central transcriptional factor involved in the cellular responses related to various aspects of cancer biology, including proliferation, survival, and angiogenesis, and the metabolism of... -
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