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Easy sedation anesthesia guide for non-anesthetic medical personnel

Min TJ

Currently, sedation anesthesia is increasingly used in many medical fields, from gastroscopy to medical imaging. The demand for sedation anesthesia is expected to increase gradually with increasing number of day...
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Monitored Anesthesia Care for Cardiovascular Interventions

Song JW, Soh S, Shim JK

The interventional cardiology is growing and evolving. Many complex procedures are now performed outside the operating room to manage cardiovascular pathologies which had been traditionally treated with cardiac surgery. Appropriate...
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Dexmedetomidine: present and future directions

Lee S

Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties. Dexmedetomidine induces a unique sedative response, which shows an easy transition from sleep...
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The effect of early extubation on postoperative delirium in patients with liver transplantation: a propensity score matching analysis

Choi YM, Choi YJ, Choi EJ, Ri HS, Park JY, Koh KH, Yoon SZ, Cha JR, Lee KS

BACKGROUND: Maintenance of tracheal intubation is associated with use of sedatives, stress due to mechanical ventilation, or respiratory complications. The aim of this study is to compare the incidence of...
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Survey of Knowledge on Insomnia for Sleep Clinic Clients

Soh M

OBJECTIVES: Insomnia is not only the most common sleep-related disorder, but also is one of the most important. Knowledge of the comorbidities of insomnia is essential for proper treatment including...
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Evaluation of Acute and Sub-acute Oral Toxicity Effect of Aquilaria malaccensis Leaves Aqueous Extract in Male ICR Mice

Musa NH, Zain HH, Ibrahim H, Jamil NN

The study was conducted to investigate the acute and sub-acute toxicity effect of Aquilaria malaccensis leaves aqueous extract (AEAM) towards male ICR mice in terms of body weight, relative organ...
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Clinical Characteristics and Psychotropic Drug Prescription Patterns of Bipolar Disorder Patients with a History of Suicidal Attempts: Findings from the REAP-BD, Korea

Park SC, Kim K, Jang OJ, Kim SG, Lee JG, Park JH, Choi J, Lee DW, Lin SK, Tan CH, Shinfuku N, Park YC

Our study aimed to analyze the clinical characteristics and psychotropic prescription patterns of a history of suicide attempts in South Koreans with bipolar disorder (BD), by using only Korean data...
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Sedation Strategies for Procedures Outside the Operating Room

Jo YY, Kwak HJ

With the rapid development of diagnostic and therapeutic procedures performed outside the operating room (OR), the need for appropriate sedation care has emerged in importance to ensure the safety and...
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Propofol with and without Midazolam for Diagnostic Upper Gastrointestinal Endoscopies in Children

Akbulut UE, Kartal S, Dogan U, Akcali GE, Kalayci S, Kirci H

PURPOSE: Various publications on the use of sedation and anesthesia for diagnostic procedures in children have demonstrated that no ideal agent is available. Although propofol has been widely used for...
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The correlation of heart rate between natural sleep and dexmedetomidine sedation

Kang D, Lim C, Shim DJ, Kim H, Kim JW, Chung HJ, Shin Y, Kim JD, Ryu SJ

BACKGROUND: Sedation by dexmedetomidine, like natural sleep, often causes bradycardia. We explored the nature of heart rate (HR) changes as they occur during natural sleep versus those occurring during dexmedetomidine...
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Role of dexmedetomidine in pediatric dental sedation

Mohite V, Baliga S, Thosar N, Rathi N

Dexmedetomidine is a highly selective α2-adrenoceptor agonist with a vast array of properties, making it suitable for sedation in numerous clinical scenarios. Its use was previously restricted to the sedation...
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Comorbid Zolpidem Dependence and Over-the-Counter Compound Analgesic Abuse

Kim H, Shin C, Ko YH, Han C

Zolpidem is a commonly prescribed hypnotic used to treat insomnia. However, its potential for abuse and dependence has recently become controversial. Although over-the-counter (OTC) medications are widely used, their abuse...
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Predicting the Outcome of Critically Ill Children and Adolescents with Electroencephalography

Lee S, Ko A, Sol IS, Kim KW, Kang HC, Lee JS, Kim HD, Kim SH

PURPOSE: Electroencephalography (EEG) is an effective test in predicting severe cortical dysfunction associated with poor outcomes in adult patients, but its value in pediatric patients remains incomplete. Here, we assessed...
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Development of Safety Usage Guidelines for Sedative Hypnotics Using the Delphi Technique

Nam YJ, Cho CH, Lee Y, Lee HJ

OBJECTIVES: The objective of this study was to develop evidence- and consensus-based clinical safety usage guidelines for sedative hypnotics using the Delphi technique. METHODS: A group of 15 sleep experts from...
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The Effect of a Sleep Education and Hypnotics Reduction Program on Hypnotics Prescription Rate for the Hospitalized Patients with Cancer at a General Hospital

Youn S, Lee S, Kim C, Chung S

OBJECTIVE: We aimed to investigate whether the sleep education and hypnotics reduction program (the i-sleep program), developed for all hospitalized patients and medical personnel, help reducing the hypnotics prescriptions rate...
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Using Etomidate and Midazolam for Screening Colonoscopies Results in More Stable Hemodynamic Responses in Patients of All Ages

Lee JM, Min G, Keum B, Lee JM, Kim SH, Choi HS, Kim ES, Seo YS, Jeen YT, Chun HJ, Lee HS, Um SH, Kim CD

BACKGROUND/AIMS: Recent studies have demonstrated that etomidate is a safe sedative drug with noninferior sedative effects. In our recent study, we revealed that etomidate/midazolam was more hemodynamically stable than propofol/midazolam...
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Sleep Promoting Effect of Luteolin in Mice via Adenosine A1 and A2A Receptors

Kim TH, Custodio R, Cheong JH, Kim HJ, Jung YS

Luteolin, a widespread flavonoid, has been known to have neuroprotective activity against various neurologic diseases such as epilepsy, and Alzheimer’s disease. However, little information is available regarding the hypnotic effect...
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Inhalation Sedation: A Systematic Review and Meta-Analysis

Mo J

PURPOSE: The safety and effectiveness of inhalation sedation, a technique that enables sedation using the inhalation of an anesthetic in an out-of-theater environment was evaluated in this study. METHODS: Electronic literature...
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3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABA(A)-benzodiazepine Receptors

Woo J, Yang H, Yoon M, Gadhe CG, Pae AN, Cho S, Lee CJ

3-Carene, a bicyclic monoterpene, is one of the major components of the pine tree essential oils. It has been reported that, in addition to its known properties as a phytoncide,...
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The potential of earthworm and its components as a therapeutic agent for neuronal damage

Moon BC, Kim JS

Earthworms have been employed in traditional oriental medicine for the treatment of neurological disorders, as anticonvulsants, analgesics, and sedatives. In fact, earthworms are currently used as a medicinal agent in...
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