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Pharmacology of Intracisternal or Intrathecal Glycine, Muscimol, and Baclofen in Strychnine-induced Thermal Hyperalgesia of Mice

Lee IO, Son JK, Lim ES, Kim YS

Glycine and gamma-aminobutyric acid (GABA) are localized and released by the same interneurons in the spinal cord. Although the effects of glycine and GABA on analgesia are well known, little...
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Analgesic Effects of Dexmedetomidine in Vincristine-Evoked Painful Neuropathic Rats

Park HJ, Kim YH, Koh HJ, Park CS, Kang SH, Choi JH, Moon DE

Dexmedetomidine, which is a selective alpha2-adrenoceptor agonist, was recently introduced into clinical practice for its analgesic properties. The purpose of this study was to evaluate the effects of dexmedetomidine in...
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