- Decreased Expression of Type 5 17beta-Hydroxysteroid Dehydrogenase (AKR1C3) Protein Identified in Human Diabetic Skin Tissue
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Cho MK
- KMID: 2265048
- Ann Dermatol.
- 2013 Nov;25(4):423-427.
- doi: 10.5021/ad.2013.25.4.423
BACKGROUND: Diabetes is characterized by chronic hyperglycemia, and hyperglycemia can increase reactive oxygen species (ROS) production from the mitochondrial electron transport chain. The formation of ROS in cells induces oxidative... -
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- Altered Regulation of 11beta-hydroxysteroid Dehydrogenase II in the Kidney of Rats with Experimental Hypertension
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Kang SS, Kim SW, Lee JU
- KMID: 2052290
- Electrolyte Blood Press.
- 2007 Dec;5(2):89-94.
- doi: 10.5049/EBP.2007.5.2.89
The present study was aimed at investigating the role of type II 11beta-hydroxysteroid dehydrogenase (IIbeta- HSD II) in the development of hypertension. Two-kidney, one-clip (2K1C), deoxycorticosterone acetate (DOCA)/salt, or NG-nitro-L-arginine... -
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- Licorice Induced Hypokalemia
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Cho S, Lim B, Cho H, Joung J, Choi Y, Kim D, Shin G, Kim H
- KMID: 2079205
- Korean J Nephrol.
- 2001 Nov;20(6):1021-1025.
A high intake of licorice can cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure and depression of renin-angiotensin-aldosterone system. Glycyrrhizic acid, a component of licorice, produces... -
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- A Case of Licorice-Induced Hypokalemic Rhabdomyolysis in a Patient Using a Diuretic Drug
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Park KA, Seok SJ, Kim SJ, Gil HW, Yang JO, Lee EY, Hong SY
- KMID: 2258900
- Korean J Med.
- 2011 Jun;80(Suppl 2):S258-S262.
Glycyrrhizic acid is a component of licorice. It can cause hypokalemia through the inhibition of 11beta-hydroxysteroid dehydrogenase. The severity of symptoms depends on the dose and duration of licorice intake,... -
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- Mitochondrial Dysfunction in Adipocytes as a Primary Cause of Adipose Tissue Inflammation
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Woo CY, Jang JE, Lee SE, Koh EH, Lee KU
- KMID: 2454054
- Diabetes Metab J.
- 2019 Jun;43(3):247-256.
- doi: 10.4093/dmj.2018.0221
Adipose tissue inflammation is considered a major contributing factor in the development of obesity-associated insulin resistance and cardiovascular diseases. However, the cause of adipose tissue inflammation is presently unclear. The... -
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- Dysregulation of ENaC in Animal Models of Nephrotic Syndrome and Liver Cirrhosis
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Kim SW
- KMID: 2052266
- Electrolyte Blood Press.
- 2006 Mar;4(1):23-34.
- doi: 10.5049/EBP.2006.4.1.23
Nephrotic syndrome and liver cirrhosis are common clinical manifestations, and are associated with avid sodium retention leading to the development of edema and ascites. However, the mechanism for the sodium... -
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- Pathophysiology and clinical characteristics of hypothalamic obesity in children and adolescents
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Kim JH, Choi JH
- KMID: 2266349
- Ann Pediatr Endocrinol Metab.
- 2013 Dec;18(4):161-167.
- doi: 10.6065/apem.2013.18.4.161
The hypothalamus plays a key role in the regulation of body weight by balancing the intake of food, energy expenditure, and body fat stores, as evidenced by the fact that... -
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- The effects of the standardized extracts of Ginkgo biloba on steroidogenesis pathways and aromatase activity in H295R human adrenocortical carcinoma cells
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Kim M, Park YJ, Ahn H, Moon B, Chung KH, Oh SM
- KMID: 2469666
- Environ Health Toxicol.
- 2016 ;31(1):e2016010.
- doi: 10.5620/eht.e2016010
OBJECTIVES: Aromatase inhibitors that block estrogen synthesis are a proven first-line hormonal therapy for postmenopausal breast cancer. Although it is known that standardized extract of Ginkgo biloba (EGb761) induces anti-carcinogenic... -
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