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Pharmacological Unmasking Microarray Approach-Based Discovery of Novel DNA Methylation Markers for Hepatocellular Carcinoma

Jung N, Won JK, Kim BH, Suh KS, Jang JJ, Kang GH

DNA methylation is one of the main epigenetic mechanisms and hypermethylation of CpG islands at tumor suppressor genes switches off these genes. To find novel DNA methylation markers in hepatocellular...
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ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response

Jang ER, Choi JD, Park MA, Jeong G, Cho H, Lee JS

Chromatin structure has a crucial role in a diversity of physiological processes, including development, differentiation and stress responses, via regulation of transcription, DNA replication and DNA damage repair. Histone deacetylase...
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