- Bilirubin Activates Transcription of HIF-1alpha in Human Proximal Tubular Cells Cultured in the Physiologic Oxygen Content
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Kim SG, Ahn SY, Lee ES, Kim S, Na KY, Chae DW, Chin HJ
- KMID: 2069806
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S146-S154.
- doi: 10.3346/jkms.2014.29.S2.S146
The expression of hypoxia-inducible factor (HIF) is influenced by reactive oxygen species (ROS). Effect of bilirubin on HIF-1 expression in proximal tubular cells was investigated under physiological oxygen concentration, which... -
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- Effects of Chromosomal Polyploidy on Survival of Colon Cancer Cells
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Park SU, Choi ES, Jang YS, Hong SH, Kim IH, Chang DK
- KMID: 1128353
- Korean J Gastroenterol.
- 2011 Mar;57(3):150-157.
- doi: 10.4166/kjg.2011.57.3.150
BACKGROUND/AIMS: Tetraploid cells are frequently observed in the inflamed mucosal epithelial cells of the patients with Barrett's esophagus or chronic ulcerative colitis. Polyploidy often occurs during cell fusion, abortive cell... -
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- Effects of Bevacizumab on Bcl-2 Expression and Apoptosis in Retinal Pigment Epithelial Cells under Oxidative Stress
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Kim S, Kim YJ, Kim NR, Chin HS
- KMID: 2363851
- Korean J Ophthalmol.
- 2015 Dec;29(6):424-432.
- doi: 10.3341/kjo.2015.29.6.424
PURPOSE: To evaluate the effects of bevacizumab on expression of B-cell leukemia/lymphoma (Bcl)-2 and apoptosis in retinal pigment epithelial (RPE) cells under oxidative stress conditions. METHODS: RPE cells were treated with... -
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- Exendin-4 Protects Oxidative Stress-Induced beta-Cell Apoptosis through Reduced JNK and GSK3beta Activity
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Kim JY, Lim DM, Moon CI, Jo KJ, Lee SK, Baik HW, Lee KH, Lee KW, Park KY, Kim BJ
- KMID: 1779233
- J Korean Med Sci.
- 2010 Nov;25(11):1626-1632.
- doi: 10.3346/jkms.2010.25.11.1626
Oxidative stress induced by chronic hyperglycemia in type 2 diabetes plays a crucial role in progressive loss of beta-cell mass through beta-cell apoptosis. Glucagon like peptide-1 (GLP-1) has effects on... -
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