- Consistent and Specific Suppression of Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells by Poly-L-Lysine
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Lee CJ, Lee JH, Seok JH, Hur GM, Park JS, Bae S, Jang HS, Park SC
- KMID: 2071588
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):143-147.
Poly-L-lysine (PLL) was reported to suppress mucin release from airway goblet cells during 30 min treatment period. In this study, we investigated whether PLL consistently suppresses mucin release from cultured... -
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- Effects of Proinflammatory Cytokines and Natural Products on Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells
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Park JS, Kim HS, Seok JH, Hur GM, Park JS, Seo UK, Lee CJ
- KMID: 1611491
- Korean J Physiol Pharmacol.
- 2004 Dec;8(6):329-333.
In this study, we investigated whether TNF-alpha, IL-1beta, CTMA (carboxymethyl trimethylammonium) and LPD (Lup-20[29]-ene-3beta, 28-diol) affect mucin release from airway goblet cells and compared the activities of these agents with... -
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- Caffeic Acid Phenethyl Ester Inhibits the PKC-Induced IL-6 Gene Expression in the Synoviocytes of Rheumatoid Arthritis Patients
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Hur GM, Hwang YB, Lee JH, Bae SH, Park JS, Lee CJ, Seok JH
- KMID: 1607522
- Korean J Physiol Pharmacol.
- 2003 Dec;7(6):363-368.
To gain insight on the role of pro-inflammatory cytokines in the pathogenesis and treatment of rheumatoid arthritis (RA), the phorbol 12-myristate 13-acetate (PMA) -induced IL-6 gene expression and the effect... -
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- (3H)Ryanodine binding sites of SR vesicles of the chicken pectoral muscle
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Yun HY, Jeon JR, Hong JH, Hur GM, Lee JH, Seok JH
- KMID: 2071509
- Korean J Physiol Pharmacol.
- 1997 Aug;1(4):377-384.
To investigate the properties of ryanodine binding sites of the bird skeletal SR vesicles, SDS PAGE, purification of RyR, and (3H)ryanodine binding study were carried out in the SR vesicles prepared from... -
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- Diclofenac inhibits IFN-gamma plus lipopolysaccharide-induced iNOS gene expression via suppression of NF-kappaB activation in RAW 264.7 macrophages
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Bae SH, Ryu YS, Hong JH, Park JC, Kim YM, Seok JH, Lee JH, Hur GM
- KMID: 1607141
- Korean J Physiol Pharmacol.
- 2001 Dec;5(6):521-527.
Diclofenac, a phenylacetic acid derivative, is a widely used non-steroidal anti-inflammatory drug (NSAID) to provide effective relief of inflammation and pain. Nitric oxide (NO) synthesized by inducible nitric oxide synthase... -
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- Expression Changes of Endothelin-1, Endothelin Receptor A and B in the Cochlea after Noise Exposure
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Hur GM, Lyu AR, Han WK, Choi JW, Rha KS, Park YH
- KMID: 2277755
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2013 May;56(5):278-285.
- doi: 10.3342/kjorl-hns.2013.56.5.278
BACKGROUND AND OBJECTIVES: There are several evidences of reduced cochlea blood flow after noise exposure in the cochlea. However, the pathophysiology of blood flow change is still obscure, and endothelins,... -
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- Role of NF- kappaB binding sites in the regulation of inducible nitric oxide synthase by tyrosine kinase
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Ryu YS, Hong JH, Lim JH, Bae SH, Ahn IS, Seok JH, Lee JH, Hur GM
- KMID: 1606839
- Korean J Physiol Pharmacol.
- 2001 Feb;5(1):55-63.
In macrophages, lipopolysaccharide (LPS) alone or in combination with interferon- gamma (IFN- gamma) has been shown to release a nitric oxide (NO) through the increase of the transcription of the inducible nitric oxide... -
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- Disruption of Microtubules Sensitizes the DNA Damage-induced Apoptosis Through Inhibiting Nuclear Factor kappaB (NF-kappaB) DNA-binding Activity
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Lee H, Jeon J, Ryu YS, Jeong JE, Shin S, Zhang T, Kang SW, Hong JH, Hur GM
- KMID: 1779226
- J Korean Med Sci.
- 2010 Nov;25(11):1574-1581.
- doi: 10.3346/jkms.2010.25.11.1574
The massive reorganization of microtubule network involves in transcriptional regulation of several genes by controlling transcriptional factor, nuclear factor-kappa B (NF-kappaB) activity. The exact molecular mechanism by which microtubule rearrangement... -
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- Long-term Activation of c-Jun N-terminal Kinase through Receptor Interacting Protein is Associated with DNA Damage-induced Cell Death
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Seok JH, Park KA, Byun HS, Won M, Shin S, Choi BL, Lee H, Kim YR, Hong JH, Park J, Hur GM
- KMID: 1838357
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):185-191.
- doi: 10.4196/kjpp.2008.12.4.185
Activation of c-Jun N-terminal kinase (JNK), a member of the mitogen-activated protein kinase family, is an important cellular response that modulates the outcome of the cells which are exposed to... -
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- Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase
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Byun HS, Won M, Park KA, Kim YR, Choi BL, Lee H, Hong JH, Piao L, Park J, Kim JM, Kweon GR, Kang SH, Han J, Hur GM
- KMID: 1052941
- Exp Mol Med.
- 2008 Apr;40(2):186-195.
- doi: 10.3858/emm.2008.40.2.186
Previous studies have demonstrated that rottlerin, a specific PKCdelta inhibitor, potentiates death receptor- mediated apoptosis through a cytochrome c-dependent or -independent pathway. However, its ability to regulate necrotic cell death,... -
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- Association between Promoter Polymorphisms of TFF1, TFF2, and TFF3 and the Risk of Gastric and Diffuse Gastric Cancers in a Korean Population
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Jin EH, Lee SI, Kim J, Seo EY, Lee SY, Hur GM, Shin S, Hong JH
- KMID: 2164496
- J Korean Med Sci.
- 2015 Aug;30(8):1035-1041.
- doi: 10.3346/jkms.2015.30.8.1035
Gastric cancer is one of the most common cancers in the world. The aims of this study were to evaluate the association between polymorphisms in TFF gene family, TFF1, TFF2,... -
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