- Inhibition of DNMT3B and PI3K/AKT/mTOR and ERK Pathways as a Novel Mechanism of Volasertib on Hypomethylating Agent-Resistant Cells
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Choi EJ, Koo BK, Hur EH, Moon JH, Kim JY, Park HS, Choi Y, Lee KH, Lee JH, Choi EK, Lee JH
- KMID: 2541791
- Biomol Ther.
- 2023 May;31(3):319-329.
- doi: 10.4062/biomolther.2022.117
Resistance to hypomethylating agents (HMAs) in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) is a concerning problem. Polo-like kinase 1 (PLK1) is a key cell cycle modulator and is... -
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- Expression and prognostic significance of microRNAs in Korean patients with myelodysplastic syndrome
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Choi Y, Hur EH, Moon JH, Goo BK, Choi DR, Lee JH
- KMID: 2441019
- Korean J Intern Med.
- 2019 Mar;34(2):390-400.
- doi: 10.3904/kjim.2016.239
BACKGROUND/AIMS: Various alterations of microRNA (miRNA) expression have been reported in myelodysplastic syndrome (MDS). We aimed to investigate the unique patterns and prognostic significance of miRNA expression in Korean patients... -
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