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Long-term Hepatitis B Surface Antigen Profile and Seroclearance after Severe Acute Flares of Chronic Hepatitis B

Hui KY, Fung J, Cheung KS, Mak LY, Seto WK, Yuen MF

Background/Aims: Hepatitis B surface antigen (HBsAg) seroclearance remains uncommon in chronic hepatitis B (CHB) infection. During acute flares of CHB (AFOCHB), alanine aminotransferase elevation reflects a mounting immune response toward...
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Apatinib Combined with Local Irradiation Leads to Systemic TumorControl via Reversal of Immunosuppressive Tumor Microenvironmentin Lung Cancer

Liang Lj, Hu Cx, Wen Yx, Geng Xw, Chen T, Gu Gq, Wang L, Xia Yy, Liu Y, Fei Jy, Dong J, Zhao Fh, Ahongjiang Y, Hui Ky, Jiang Xd

Purpose This study aimed to investigate the potential systemic antitumor effects of stereotactic ablative radiotherapy (SABR) and apatinib (a novel vascular endothelial growth factor receptor 2 inhibitor) via reversing the immunosuppressive tumor microenvironment...
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