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Intravenous patient-controlled analgesia hydromorphone combined with pregabalin for the treatment of postherpetic neuralgia: a multicenter, randomized controlled study

Huang Y, Xu C, Zeng T, Li Z, Xia Y, Tao G, Zhu T, Lu L, Li J, Huang T, Huai H, Ning B, Ma C, Wang X, Chang Y, Mao P, Lin J

Background: Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The treatment of PHN remains a challenge for clinical pain management. Despite the effectiveness of anticonvulsants, antidepressants,...
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Sinapic Acid Attenuates the Neuroinflammatory Response by Targeting AKT and MAPK in LPS-Activated Microglial Models

Huang T, Zhao D, Lee S, Keum G, Yang HO

Sinapic acid (SA) is a phenolic acid that is widely distributed in fruits and vegetables, which has various bioactivities, such as antidiabetic, anticancer and anti-inflammatory functions. Over-activated microglial is involved...
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Parathyroid Hormone-Related Protein Promotes the Proliferation of Patient-Derived Glioblastoma Stem Cells via Activating cAMP/PKA Signaling Pathway

Guo Z, Huang T, Liu Y, Liu C

Background and Objectives: Glioblastoma (GBM) is an aggressive primary brain tumor characterized by its hetero-geneity and high recurrence and lethality rates. Glioblastoma stem cells (GSCs) play a crucial role in...
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Combined Application of Dentin Noncollagenous Proteins and Odontogenic Biphasic Calcium Phosphate in Rabbit Maxillary Sinus Lifting

Yang G, Liu X, Huang T, Ding R, Wang Y

BACKGROUND: Teeth can be used as a raw material for preparing bone substitutes due to their similar chemical composition to bone. The objective of our study was to evaluate the...
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Intracellular trafficking of TREM2 is regulated by presenilin 1

Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H

Genetic mutations in triggering receptor expressed on myeloid cells 2 (TREM2) have been linked to a variety of neurodegenerative diseases including Alzheimer’s disease, amyotrophic lateral sclerosis, frontotemporal dementia and Parkinson’s...
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The Role of Inflammatory Mediators in the Pathogenesis of Otitis Media and Sequelae

Juhn SK, Jung MK, Hoffman MD, Drew BR, Preciado D, Sausen NJ, Jung TT, Kim BH, Park SY, Lin J, Ondrey FG, Mains DR, Huang T

This review deals with the characteristics of various inflammatory mediators identified in the middle ear during otitis media and in cholesteatoma. The role of each inflammatory mediator in the pathogenesis...
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Correlations of Four Genetic Single Nucleotide Polymorphisms in Brain-Derived Neurotrophic Factor with Posttraumatic Stress Disorder

Guo JC, Yang YJ, Guo M, Wang XD, Juan Y, Gao YS, Fu LQ, Jiang XL, Fu LM, Huang T

OBJECTIVE: To investigate the correlations of four genetic single nucleotide polymorphisms (SNPs) of brain-derived neurotrophic factor (BDNF) with posttraumatic stress disorder (PTSD). METHODS: A total of 300 patients with sporadic PTSD...
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Transitional Zone Index and Intravesical Prostatic Protrusion in Benign Prostatic Hyperplasia Patients: Correlations according to Treatment Received and Other Clinical Data

Huang T, Qi J, Yu Y, Xu D, Jiao Y, Kang J, Zhu Y, Chen Y

  • KMID: 2315387
  • Korean J Urol.
  • 2012 Apr;53(4):253-257.
PURPOSE: The aim of this research was to assess the value of the transitional zone index (TZI) and intravesical prostatic protrusion (IPP) from transrectal ultrasonography in evaluating the severity and...
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Nail DNA and Possible Biomarkers: A Pilot Study

Park J, Liang D, Kim JW, Luo Y, Huang T, Kim SY, Chang SS

OBJECTIVES: Nail has been a substitute DNA source for genotyping. To investigate the integrity and consistency of nail DNA amplification for biomarker study, nail clippings from 12 subjects were collected...
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Pim-1 Protects Retinal Ganglion Cells by Enhancing Their Regenerative Ability Following Optic Nerve Crush

Zhang S, Shuai L, Wang D, Huang T, Yang S, Miao M, Liu F, Xu J

  • KMID: 2503984
  • Exp Neurobiol.
  • 2020 Jun;29(3):249-272.
  • doi: 10.5607/en20019
Provirus integration site Moloney murine leukemia virus (Pim-1) is a proto-oncogene reported to be associated with cell proliferation, differentiation and survival. This study was to explore the neuroprotective role of...
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